Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetBeta-secretase 1(Homo sapiens (Human))
Wyeth

Curated by ChEMBL

LigandBDBM50315009(4-(1-((6-aminopyridin-2-yl)methyl)-5-phenyl-1H-pyr...)Copy SMILESCopy InChI

Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of human recombinant BACE1 expressed CHO cells by FRET assayMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetCathepsin D(Homo sapiens (Human))
Wyeth

Curated by ChEMBL

LigandBDBM50315009(4-(1-((6-aminopyridin-2-yl)methyl)-5-phenyl-1H-pyr...)Copy SMILESCopy InChI

Affinity DataIC50:  4.43E+4nMAssay Description:Inhibition of cathepsin D by FRET assayMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI