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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
4
hits in this display
Target
Acetyl-CoA carboxylase 2
(Homo sapiens (Human))
Pfizer
US Patent
Ligand
BDBM50439646
(CHEMBL2419600 | US8993586, 110)
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Affinity Data
IC50: 1.10nM
Assay Description:
Preparation of rhACC2. Human ACC2 inhibition was measured using purified recombinant human ACC2 (hrACC2). Briefly, a full length Cytomax clone of ACC...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
US Patent
Copy BDB DOI
Target
Acetyl-CoA carboxylase 2
(Homo sapiens (Human))
Pfizer
US Patent
Ligand
BDBM50439646
(CHEMBL2419600 | US8993586, 110)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.70nM
Assay Description:
Inhibition of human ACC2 using acetyl-CoA as substrate assessed as [14C]malonyl-CoA synthesis preincubated for 10 mins prior to substrate addition me...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Acetyl-CoA carboxylase 1
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50439646
(CHEMBL2419600 | US8993586, 110)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.80nM
Assay Description:
Inhibition of human ACC1 using acetyl-CoA as substrate assessed as [14C]malonyl-CoA synthesis preincubated for 10 mins prior to substrate addition me...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Acetyl-CoA carboxylase 1
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50439646
(CHEMBL2419600 | US8993586, 110)
Copy SMILES
Copy InChI
Affinity Data
IC50: 5.60nM
pH: 7.5
Assay Description:
Preparation of rhACC1. Two liters of SF9 cells, infected with recombinant baculovirus containing full length human ACC1 cDNA, were suspended in ice-c...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
US Patent
Copy BDB DOI