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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetLIM domain kinase 1(Homo sapiens (Human))
Cancer Research Technology

Curated by ChEMBL
LigandPNGBDBM50124356(CHEMBL3622867)
Affinity DataIC50:  15nMAssay Description:Inhibition of recombinant N-terminal 6His-tagged LIMK1 (unknown origin) expressed in Sf21 cells by HTRF assay using cofilin as a substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLIM domain kinase 1(Homo sapiens (Human))
Cancer Research Technology

Curated by ChEMBL
LigandPNGBDBM50124356(CHEMBL3622867)
Affinity DataIC50:  15nMAssay Description:Inhibition of human LIMK1 (321 to 647 residues) expressed in Sf9 cells using dextrin as substrate incubated for 30 mins by micro-scintillation fluid ...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetLIM domain kinase 1(Homo sapiens (Human))
Cancer Research Technology

Curated by ChEMBL
LigandPNGBDBM50124356(CHEMBL3622867)
Affinity DataIC50:  3.80E+3nMAssay Description:Inhibition of LIMK1 in human ZR75-1 cells assessed as inhibition of cofilin phosphorylation after 5 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed