Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 5 hits in this display   

TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50071172(9-Methoxy-2-methyl-11,12-dihydro-3H,6aH,13H-6-oxa-...)
Affinity DataIC50:  360nMAssay Description:Evaluated for its binding affinity at human muscarinic receptor m4 by the displacement of [3H]NMS binding using membranes from transfected chinese ha...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50071172(9-Methoxy-2-methyl-11,12-dihydro-3H,6aH,13H-6-oxa-...)
Affinity DataIC50:  1.48E+3nMAssay Description:Evaluated for its binding affinity at human muscarinic receptor m3 by the displacement of [3H]NMS binding using membranes from transfected chinese ha...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50071172(9-Methoxy-2-methyl-11,12-dihydro-3H,6aH,13H-6-oxa-...)
Affinity DataIC50:  1.91E+3nMAssay Description:Evaluated for its binding affinity at human muscarinic receptor m2 by displacement of [3H]NMS binding using membranes from transfected chinese hamste...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50071172(9-Methoxy-2-methyl-11,12-dihydro-3H,6aH,13H-6-oxa-...)
Affinity DataIC50:  1.96E+3nMAssay Description:Evaluated for its binding affinity at human muscarinic receptor m1 by displacement of [3H]NMS binding using membranes in transfected chinese hamster ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M5(Homo sapiens (Human))
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50071172(9-Methoxy-2-methyl-11,12-dihydro-3H,6aH,13H-6-oxa-...)
Affinity DataIC50:  3.81E+3nMAssay Description:Evaluated for its binding affinity at human muscarinic receptor m5 by the displacement of [3H]NMS binding using membranes from transfected chinese ha...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed