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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
4
hits in this display
Target
Kappa-type opioid receptor
(Homo sapiens (Human))
Adolor
Curated by
ChEMBL
Ligand
BDBM50166626
(CHEMBL363822 | N-[(S)-2-((S)-3-Hydroxy-pyrrolidin-...)
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Affinity Data
Ki: 1.30nM
Assay Description:
Inhibitory constant against human Opioid receptor kappa using [3H]-diprenorphine as radio ligand
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Delta-type opioid receptor
(Homo sapiens (Human))
Adolor
Curated by
ChEMBL
Ligand
BDBM50166626
(CHEMBL363822 | N-[(S)-2-((S)-3-Hydroxy-pyrrolidin-...)
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Affinity Data
Ki: 124nM
Assay Description:
Inhibitory constant against human Opioid receptor delta 1 using [3H]diprenorphine as radio ligand
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mu-type opioid receptor
(Homo sapiens (Human))
Adolor
Curated by
ChEMBL
Ligand
BDBM50166626
(CHEMBL363822 | N-[(S)-2-((S)-3-Hydroxy-pyrrolidin-...)
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Affinity Data
Ki: 1.05E+3nM
Assay Description:
Inhibitory constant against human Opioid receptor mu 1 using [3H]diprenorphine as radio ligand
More data for this Ligand-Target Pair
Target Info
PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Kappa-type opioid receptor
(Homo sapiens (Human))
Adolor
Curated by
ChEMBL
Ligand
BDBM50166626
(CHEMBL363822 | N-[(S)-2-((S)-3-Hydroxy-pyrrolidin-...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 4.60nM
Assay Description:
Agonist activity assessed by ability to stimulate [35S]GTP gammaS binding to opioid receptor kappa in human membranes
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI