Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetKappa-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL

LigandBDBM50174952((S)-N-((S)-2-((S)-3-hydroxypyrrolidin-1-yl)-1-phen...)Copy SMILESCopy InChI

Affinity DataKi:  14nMAssay Description:Agonistic activity at kappa opioid receptorMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetMu-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL

LigandBDBM50174952((S)-N-((S)-2-((S)-3-hydroxypyrrolidin-1-yl)-1-phen...)Copy SMILESCopy InChI

Affinity DataKi: >5.00E+3nMAssay Description:Agonistic activity at mu opioid receptorMore data for this Ligand-Target Pair

Target InfoPDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetCytochrome P450 2D6(Homo sapiens (Human))
Adolor

Curated by ChEMBL

LigandBDBM50174952((S)-N-((S)-2-((S)-3-hydroxypyrrolidin-1-yl)-1-phen...)Copy SMILESCopy InChI

Affinity DataIC50:  9.50E+3nMAssay Description:Inhibitory activity against CYP2D6More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI