Home
About
Info
Download
WebServices
Contact
Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
8
hits in this display
Target
Adenosine receptor A2a
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM50125929
(2-(furan-2-yl)-8-methyl-9-(propylthio)-8H-pyrazolo...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 2.10nM
Assay Description:
Displacement of [3H]NECA from human adenosine A2A receptor expressed in CHO cells
Checked by Author
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Adenosine receptor A2a
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM50125929
(2-(furan-2-yl)-8-methyl-9-(propylthio)-8H-pyrazolo...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 2.10nM
Assay Description:
Displacement of [3H]SCH-58261 from human Adenosine A2A receptor expressed in CHO cells
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Adenosine receptor A1
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM50125929
(2-(furan-2-yl)-8-methyl-9-(propylthio)-8H-pyrazolo...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 9nM
Assay Description:
Displacement of [3H]- DPCPX binding at human Adenosine A1 receptor expressed in CHO cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Adenosine receptor A2b
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM50125929
(2-(furan-2-yl)-8-methyl-9-(propylthio)-8H-pyrazolo...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 69nM
Assay Description:
Displacement of [3H]- DPCPX from human adenosine A2B receptor expressed in HEK293 cells
More data for this Ligand-Target Pair
Target Info
PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Adenosine receptor A3
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM50125929
(2-(furan-2-yl)-8-methyl-9-(propylthio)-8H-pyrazolo...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 224nM
Assay Description:
Displacement of [3H]NECA from human adenosine A3 receptor expressed in CHO cells
Checked by Author
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Adenosine receptor A3
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM50125929
(2-(furan-2-yl)-8-methyl-9-(propylthio)-8H-pyrazolo...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 224nM
Assay Description:
Displacement of [3H]- MRE 308F20 binding from human Adenosine A3 receptor expressed in CHO cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Adenosine receptor A2a
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM50125929
(2-(furan-2-yl)-8-methyl-9-(propylthio)-8H-pyrazolo...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 14.8nM
Assay Description:
Antagonist activity as inhibition of cAMP generation after agonist-modulation of human Adenosine A2A receptor with 100 nM NECA
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Adenosine receptor A3
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM50125929
(2-(furan-2-yl)-8-methyl-9-(propylthio)-8H-pyrazolo...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 852nM
Assay Description:
Antagonist activity as inhibition of cAMP generation after agonist-modulation of Adenosine A3 receptor with 100 nM CI-IB-MECA
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI