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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50178263(CHEMBL3814350)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of human His6-tagged PDK1 using biotinylated PDKtide as substrate after 60 mins by topcount methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50178263(CHEMBL3814350)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of PDK1 in human PC3 cells assessed as reduction in AKT Thr308 phosphorylation after 45 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed