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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
6
hits in this display
Target
Sodium-dependent serotonin transporter
(Homo sapiens (Human))
Green Cross
US Patent
Ligand
BDBM50352660
(CHEMBL1823074 | US8835436, Example 135)
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Affinity Data
IC50: 10.2nM
pH: 7.4
Assay Description:
For serotonin transporter binding assays, a reaction mixture with a final volume of 0.25 ml was prepared by mixing a test compound, human serotonin t...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
US Patent
Copy BDB DOI
Target
Sodium-dependent serotonin transporter
(Homo sapiens (Human))
Green Cross
US Patent
Ligand
BDBM50352660
(CHEMBL1823074 | US8835436, Example 135)
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Copy InChI
Affinity Data
IC50: 10.2nM
Assay Description:
Displacement of [3H]impiramine from human serotonin transporter membrane expressed in HEK293 cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
5-hydroxytryptamine receptor 2A
(Homo sapiens (Human))
Green Cross
Curated by
ChEMBL
Ligand
BDBM50352660
(CHEMBL1823074 | US8835436, Example 135)
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Affinity Data
IC50: 15.2nM
Assay Description:
Displacement of [3H]ketanserin from human recombinant serotonin 5-HT2A receptor expressed in CHO-K1 cells
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 2A
(Homo sapiens (Human))
Green Cross
Curated by
ChEMBL
Ligand
BDBM50352660
(CHEMBL1823074 | US8835436, Example 135)
Copy SMILES
Copy InChI
Affinity Data
IC50: 15.2nM
pH: 7.4
Assay Description:
For serotonin 5-HT2A binding, an aliquot of human recombinant serotonin 5-HT2A receptor (PerkinElmer Life and Analytical Sciences, USA) expressed in ...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
US Patent
Copy BDB DOI
Target
5-hydroxytryptamine receptor 2C
(Homo sapiens (Human))
Green Cross
Curated by
ChEMBL
Ligand
BDBM50352660
(CHEMBL1823074 | US8835436, Example 135)
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Copy InChI
Affinity Data
IC50: 204nM
Assay Description:
Displacement of [3H]mesulergine from human recombinant 5-HT2C receptor expressed in CHO-K1 cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 2C
(Homo sapiens (Human))
Green Cross
Curated by
ChEMBL
Ligand
BDBM50352660
(CHEMBL1823074 | US8835436, Example 135)
Copy SMILES
Copy InChI
Affinity Data
IC50: 204nM
pH: 7.4
Assay Description:
For serotonin 5-HT2A binding, an aliquot of human recombinant serotonin 5-HT2A receptor (PerkinElmer Life and Analytical Sciences, USA) expressed in ...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
US Patent
Copy BDB DOI