Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetType-1 angiotensin II receptor A/B(RAT)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL

LigandBDBM50125345(3-[2'-(3,4-Dimethyl-isoxazol-5-ylsulfamoyl)-2-meth...)Copy SMILESCopy InChI

Affinity DataKi:  4nMAssay Description:Binding affinity towards Angiotensin II receptor, type 1 in rat aortic smooth muscle cells using 0.2 nM [125I]-labeled Sar-Ile-angiotensin IIMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetEndothelin-1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL

LigandBDBM50125345(3-[2'-(3,4-Dimethyl-isoxazol-5-ylsulfamoyl)-2-meth...)Copy SMILESCopy InChI

Affinity DataKi:  5nMAssay Description:Binding affinity towards human ETA receptor expressed in CHO-K1 cells in the presence of 0.05 nM [125I]-labeled endothelin 1More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI