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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
6
hits in this display
Target
Sodium-dependent serotonin transporter
(Homo sapiens (Human))
Green Cross
Curated by
ChEMBL
Ligand
BDBM50313252
(CHEMBL1080728 | N-(3-(4-(3-chlorophenyl)piperazin-...)
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Affinity Data
IC50: 93nM
Assay Description:
Displacement of [3H]imipramine from human SERT expressed in HEK293 cells after 30 mins by rapid filtration assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Sodium-dependent serotonin transporter
(Homo sapiens (Human))
Green Cross
Curated by
ChEMBL
Ligand
BDBM50313252
(CHEMBL1080728 | N-(3-(4-(3-chlorophenyl)piperazin-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 93nM
Assay Description:
Displacement of [3H]imipramine from human SERT expressed in HEK293 cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 2A
(Homo sapiens (Human))
Green Cross
Curated by
ChEMBL
Ligand
BDBM50313252
(CHEMBL1080728 | N-(3-(4-(3-chlorophenyl)piperazin-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 191nM
Assay Description:
Displacement of [3H]ketanserin from human recombinant 5HT2A expressed in CHOK1 cells
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 2A
(Homo sapiens (Human))
Green Cross
Curated by
ChEMBL
Ligand
BDBM50313252
(CHEMBL1080728 | N-(3-(4-(3-chlorophenyl)piperazin-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 191nM
Assay Description:
Displacement of [3H]ketanserin from human recombinant 5-HT2A receptor expressed in CHO-K1 cells after 60 mins
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 2C
(Homo sapiens (Human))
Green Cross
Curated by
ChEMBL
Ligand
BDBM50313252
(CHEMBL1080728 | N-(3-(4-(3-chlorophenyl)piperazin-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 273nM
Assay Description:
Displacement of [3H]mesulergine from human recombinant 5HT2C expressed in CHOK1 cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 2C
(Homo sapiens (Human))
Green Cross
Curated by
ChEMBL
Ligand
BDBM50313252
(CHEMBL1080728 | N-(3-(4-(3-chlorophenyl)piperazin-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 273nM
Assay Description:
Displacement of [3H]mesulergine from human recombinant 5-HT2C receptor expressed in CHO-K1 cells after 60 mins by rapid filtration assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI