Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetAdenosine receptor A1(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL

LigandBDBM50341187(CHEMBL1760900 | N-(7-(N-ethylacetamido)-4-methoxyb...)Copy SMILESCopy InChI

Affinity DataKi:  5nMAssay Description:Displacement of [3H]-DPCPX from human adenosine A1 receptor after 1 hrMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetAdenosine receptor A2a(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL

LigandBDBM50341187(CHEMBL1760900 | N-(7-(N-ethylacetamido)-4-methoxyb...)Copy SMILESCopy InChI

Affinity DataKi:  240nMAssay Description:Displacement of [3H]ZM241385 from human adenosine A2A receptor after 1 hrMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetAdenosine receptor A2b(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL

LigandBDBM50341187(CHEMBL1760900 | N-(7-(N-ethylacetamido)-4-methoxyb...)Copy SMILESCopy InChI

Affinity DataIC50:  18nMAssay Description:Inhibition of human adenosine A2B receptor expressed in CHO cells assessed as decrease in cellular cAMP level after 20 to 25 minsMore data for this Ligand-Target Pair

Target InfoPDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI