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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
5
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Target
N-lysine methyltransferase SMYD2
(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft
US Patent
Ligand
BDBM283169
(Rac-N-[1-{N′-cyano-N-[5-(difluoromethoxy)-2-...)
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Affinity Data
IC50: 12.5nM
pH: 9.0
Assay Description:
SMYD2 inhibitory activities of the compounds described in the present invention were quantified using a scintillation proximity assay (SPA) which mea...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
N-lysine methyltransferase SMYD2
(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft
US Patent
Ligand
BDBM283169
(Rac-N-[1-{N′-cyano-N-[5-(difluoromethoxy)-2-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 27.7nM
Assay Description:
For the detection of SMYD2 cellular methylation activity an In Cell Western (ICW) assay was established. This assay allows rapid processing of multip...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
N-lysine methyltransferase SMYD2
(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft
US Patent
Ligand
BDBM283170
(N-[1-{N′-cyano-N-[5-(difluoromethoxy)-2-meth...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 28.7nM
Assay Description:
For the detection of SMYD2 cellular methylation activity an In Cell Western (ICW) assay was established. This assay allows rapid processing of multip...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
N-lysine methyltransferase SMYD2
(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft
US Patent
Ligand
BDBM283170
(N-[1-{N′-cyano-N-[5-(difluoromethoxy)-2-meth...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 30nM
pH: 9.0
Assay Description:
SMYD2 inhibitory activities of the compounds described in the present invention were quantified using a scintillation proximity assay (SPA) which mea...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
N-lysine methyltransferase SMYD2
(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft
US Patent
Ligand
BDBM283170
(N-[1-{N′-cyano-N-[5-(difluoromethoxy)-2-meth...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >2.00E+4nM
pH: 9.0
Assay Description:
SMYD2 inhibitory activities of the compounds described in the present invention were quantified using a scintillation proximity assay (SPA) which mea...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI