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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
2
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Target
Non-specific protein-tyrosine kinase
(Homo sapiens (Human))
Dana-Farber Cancer Institute
US Patent
Ligand
BDBM196410
(US9670214, TABLE 14.4)
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Affinity Data
IC50: 742nM
pH: 7.5
Assay Description:
In vitro kinase assays were carried out by using recombinant murine c-abl containing SH3, SH2 and kinase domains (residues 46-531) and full length im...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
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Target
Non-specific protein-tyrosine kinase [T818I]
(Homo sapiens (Human))
Dana-Farber Cancer Institute
US Patent
Ligand
BDBM196410
(US9670214, TABLE 14.4)
Copy SMILES
Copy InChI
Affinity Data
IC50: 3.17E+3nM
pH: 7.5
Assay Description:
In vitro kinase assays were carried out by using recombinant murine c-abl containing SH3, SH2 and kinase domains (residues 46-531) and full length im...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI