Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetPlatelet-activating factor acetylhydrolase(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL

LigandBDBM50125274(2-[5-Chloro-2-(4-fluoro-benzylsulfanyl)-4-oxo-4H-p...)Copy SMILESCopy InChI

Affinity DataIC50:  3nMAssay Description:Inhibitory activity against recombinant human Lp-PLA2More data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
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TargetCytochrome P450 3A4(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL

LigandBDBM50125274(2-[5-Chloro-2-(4-fluoro-benzylsulfanyl)-4-oxo-4H-p...)Copy SMILESCopy InChI

Affinity DataIC50:  2.90E+4nMAssay Description:Inhibitory activity against CYP450 3A4 isozymeMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetCytochrome P450 2D6(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL

LigandBDBM50125274(2-[5-Chloro-2-(4-fluoro-benzylsulfanyl)-4-oxo-4H-p...)Copy SMILESCopy InChI

Affinity DataIC50:  8.30E+4nMAssay Description:Inhibitory activity against Cytochrome P450 2D6More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI