Home
About
Info
Download
WebServices
Contact
Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
15
hits in this display
Target
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase
(Homo sapiens (Human))
University Of Innsbruck
Curated by
ChEMBL
Ligand
BDBM55354
(CLOMIPHENE | CLOMIPHENE CITRATE | MLS000069760 | S...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 1nM
Assay Description:
Affinity for human EMP expressed in ERG2 deficient strain of Sacchromyces cerevisiae using [3H]ifenprodil or (+)-[3H]pentazocine as radioligand
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
MCE
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Sigma non-opioid intracellular receptor 1
(Homo sapiens (Human))
University Of Innsbruck
Curated by
ChEMBL
Ligand
BDBM55354
(CLOMIPHENE | CLOMIPHENE CITRATE | MLS000069760 | S...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 8nM
Assay Description:
Affinity for sigma receptor type 1 of guinea pig using [3H]ifenprodil or (+)-[3H]pentazocine radioligand
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
MCE
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
C-8 sterol isomerase ERG2
(Saccharomyces cerevisiae)
University Of Innsbruck
Curated by
ChEMBL
Ligand
BDBM55354
(CLOMIPHENE | CLOMIPHENE CITRATE | MLS000069760 | S...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 160nM
Assay Description:
Affinity for ERG2 of Sacchromyces cerevisiae using [3H]ifenprodil or (+)-[3H]pentazocine radioligand
More data for this Ligand-Target Pair
Target Info
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
MCE
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 6
(Homo sapiens (Human))
University Of North Carolina At Chapel Hill
Curated by
ChEMBL
Ligand
BDBM55354
(CLOMIPHENE | CLOMIPHENE CITRATE | MLS000069760 | S...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 1.96E+3nM
Assay Description:
Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cells after 1.5 hrs by liquid scintillation counting
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
MCE
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
NACHT, LRR and PYD domains-containing protein 3
(Homo sapiens (Human))
Burnham Center For Chemical Genomics
Curated by
PubChem BioAssay
Ligand
BDBM55354
(CLOMIPHENE | CLOMIPHENE CITRATE | MLS000069760 | S...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.41E+3nM
Assay Description:
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
Purchase
MCE
PC cid
PC sid
PDB
Similars
In Depth
Details
PCBioAssay
Copy BDB DOI
Target
Bile salt export pump
(Homo sapiens (Human))
Astrazeneca
Curated by
ChEMBL
Ligand
BDBM55354
(CLOMIPHENE | CLOMIPHENE CITRATE | MLS000069760 | S...)
Copy SMILES
Copy InChI
Affinity Data
IC50: <1.00E+4nM
Assay Description:
Inhibition of human BSEP expressed in baculovirus transfected fall armyworm Sf21 cell membranes vesicles assessed as reduction in ATP-dependent [3H]-...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
MCE
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Androgen receptor
(Rattus norvegicus (Rat))
University Of Basel
Curated by
ChEMBL
Ligand
BDBM55354
(CLOMIPHENE | CLOMIPHENE CITRATE | MLS000069760 | S...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.35E+4nM
Assay Description:
Inhibitory concentration against recombinant rat androgen receptor expressed in Escherichia coli using [3H]methyltrienolone (R 1881)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
Purchase
MCE
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Neutrophil cytosol factor 1 [S99G]
(Homo sapiens (Human))
Emory University
Curated by
PubChem BioAssay
Ligand
BDBM55354
(CLOMIPHENE | CLOMIPHENE CITRATE | MLS000069760 | S...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.63E+4nM
Assay Description:
NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Susan Smith, Emory Univers...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
Purchase
MCE
PC cid
PC sid
PDB
Similars
In Depth
Details
PCBioAssay
Copy BDB DOI
Target
Ubiquitin-conjugating enzyme E2 N
(Homo sapiens (Human))
Burnham Center For Chemical Genomics
Curated by
PubChem BioAssay
Ligand
BDBM55354
(CLOMIPHENE | CLOMIPHENE CITRATE | MLS000069760 | S...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >2.00E+4nM
Assay Description:
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego CA...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
MCE
PC cid
PC sid
PDB
Similars
In Depth
Details
PCBioAssay
Copy BDB DOI
Target
NACHT, LRR and PYD domains-containing protein 3
(Homo sapiens (Human))
Burnham Center For Chemical Genomics
Curated by
PubChem BioAssay
Ligand
BDBM55354
(CLOMIPHENE | CLOMIPHENE CITRATE | MLS000069760 | S...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.93E+4nM
Assay Description:
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
Purchase
MCE
PC cid
PC sid
PDB
Similars
In Depth
Details
PCBioAssay
Copy BDB DOI
Target
ATP-binding cassette sub-family C member 3
(Homo sapiens (Human))
Amgen
Curated by
ChEMBL
Ligand
BDBM55354
(CLOMIPHENE | CLOMIPHENE CITRATE | MLS000069760 | S...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.33E+5nM
Assay Description:
Inhibition of human MRP3 overexpressed in Sf9 insect cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
MCE
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Bile salt export pump
(Homo sapiens (Human))
Astrazeneca
Curated by
ChEMBL
Ligand
BDBM55354
(CLOMIPHENE | CLOMIPHENE CITRATE | MLS000069760 | S...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.33E+5nM
Assay Description:
Inhibition of human BSEP overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-taurocholate in presence of ATP measured after 15 to ...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
MCE
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
ATP-binding cassette sub-family C member 4
(Homo sapiens (Human))
Amgen
Curated by
ChEMBL
Ligand
BDBM55354
(CLOMIPHENE | CLOMIPHENE CITRATE | MLS000069760 | S...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.33E+5nM
Assay Description:
Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
MCE
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
ATP-binding cassette sub-family C member 2
(Homo sapiens (Human))
Amgen
Curated by
ChEMBL
Ligand
BDBM55354
(CLOMIPHENE | CLOMIPHENE CITRATE | MLS000069760 | S...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.33E+5nM
Assay Description:
Inhibition of human MRP2 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
MCE
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Heat shock factor protein 1
(Mus musculus)
Broad Institute
Curated by
PubChem BioAssay
Ligand
BDBM55354
(CLOMIPHENE | CLOMIPHENE CITRATE | MLS000069760 | S...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 1.29E+5nM
Assay Description:
Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Confirmation testing of small molecules identifie...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
Purchase
MCE
PC cid
PC sid
PDB
Similars
In Depth
Details
PCBioAssay
Copy BDB DOI