Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetApelin(Homo sapiens (Human))
University Of Strasburg

Curated by ChEMBL

LigandBDBM50009576(CHEMBL3234447)Copy SMILESCopy InChI

Affinity DataKi:  690nMAssay Description:Displacement of [125I]-pE13F from human apelin receptor expressed in CHO cell membranes after 1 hr by gamma counting analysisMore data for this Ligand-Target Pair

Target InfoReactome pathwayKEGG
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
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TargetType-1 angiotensin II receptor(Homo sapiens (Human))
University Of Strasburg

Curated by ChEMBL

LigandBDBM50009576(CHEMBL3234447)Copy SMILESCopy InChI

Affinity DataKi:  2.23E+3nMAssay Description:Displacement of [125I]-angiotensin 2 from human angiotensin 2 type-1 receptor expressed in CHO cell membranes after 1 hr by gamma counting analysisMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetApelin(Rattus norvegicus)
University Of Strasburg

Curated by ChEMBL

LigandBDBM50009576(CHEMBL3234447)Copy SMILESCopy InChI

Affinity DataIC50:  4.30E+3nMAssay Description:Agonist activity at rat apelin receptor expressed in CHO cell membranes coexpressing EGFP assessed as inhibition of forskolin-induced cAMP production...More data for this Ligand-Target Pair

Target InfoReactome pathwayKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI