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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
16
hits in this display
Target
Aurora kinase B
(Homo sapiens (Human))
Xuzhou Medical College
Curated by
ChEMBL
Ligand
BDBM50241089
(2-(ethyl(3-(4-(5-(2-(3-fluorophenylamino)-2-oxoeth...)
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Affinity Data
Ki: 0.370nM
Assay Description:
Inhibition of aurora B (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
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Target
Aurora kinase A
(Homo sapiens (Human))
Xuzhou Medical College
Curated by
ChEMBL
Ligand
BDBM50241089
(2-(ethyl(3-(4-(5-(2-(3-fluorophenylamino)-2-oxoeth...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 1.37E+3nM
Assay Description:
Inhibition of aurora A (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
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CHEMBL
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PC sid
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In Depth
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Article
PubMed
Copy BDB DOI
Target
Aurora kinase B
(Homo sapiens (Human))
Xuzhou Medical College
Curated by
ChEMBL
Ligand
BDBM50241089
(2-(ethyl(3-(4-(5-(2-(3-fluorophenylamino)-2-oxoeth...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 0.370nM
Assay Description:
Inhibition of Aurora B kinase (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
PubMed
Copy BDB DOI
Target
Aurora kinase B
(Homo sapiens (Human))
Xuzhou Medical College
Curated by
ChEMBL
Ligand
BDBM50241089
(2-(ethyl(3-(4-(5-(2-(3-fluorophenylamino)-2-oxoeth...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 0.370nM
Assay Description:
Inhibition of Aurora B (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Patents
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In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Aurora kinase A
(Homo sapiens)
Taiwan National Health Research Institutes
Curated by
ChEMBL
Ligand
BDBM50241089
(2-(ethyl(3-(4-(5-(2-(3-fluorophenylamino)-2-oxoeth...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 0.370nM
Assay Description:
Inhibition of recombinant GST-tagged N-terminal truncated human Aurora A (123 to 401 residues) expressed in Sf9 insect cell using tetra-LRRASLG pepti...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
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In Depth
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Article
PubMed
Copy BDB DOI
Target
Aurora kinase B
(Homo sapiens (Human))
Xuzhou Medical College
Curated by
ChEMBL
Ligand
BDBM50241089
(2-(ethyl(3-(4-(5-(2-(3-fluorophenylamino)-2-oxoeth...)
Copy SMILES
Copy InChI
Affinity Data
IC50: <1nM
Assay Description:
Competitive inhibition of Aurora B ATP binding site
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Patents
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In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Aurora kinase B
(Homo sapiens (Human))
Xuzhou Medical College
Curated by
ChEMBL
Ligand
BDBM50241089
(2-(ethyl(3-(4-(5-(2-(3-fluorophenylamino)-2-oxoeth...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 15.5nM
Assay Description:
In vitro kinase assay of Aurora A, B, and C using Z-LYTE technology (Invitrogen) and ATP at Km apparent for each kinase.
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
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PC sid
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In Depth
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Article
PubMed
Copy BDB DOI
Target
Aurora kinase C
(Homo sapiens (Human))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50241089
(2-(ethyl(3-(4-(5-(2-(3-fluorophenylamino)-2-oxoeth...)
Copy SMILES
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Affinity Data
IC50: 17nM
Assay Description:
Competitive inhibition of Aurora C ATP binding site
More data for this Ligand-Target Pair
Target Info
PDB
NCI pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
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CHEMBL
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PC sid
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In Depth
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Article
PubMed
Copy BDB DOI
Target
Aurora kinase C
(Homo sapiens (Human))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50241089
(2-(ethyl(3-(4-(5-(2-(3-fluorophenylamino)-2-oxoeth...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 25.3nM
Assay Description:
In vitro kinase assay of Aurora A, B, and C using Z-LYTE technology (Invitrogen) and ATP at Km apparent for each kinase.
More data for this Ligand-Target Pair
Target Info
PDB
NCI pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Aurora kinase A
(Homo sapiens (Human))
Xuzhou Medical College
Curated by
ChEMBL
Ligand
BDBM50241089
(2-(ethyl(3-(4-(5-(2-(3-fluorophenylamino)-2-oxoeth...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 193nM
Assay Description:
In vitro kinase assay of Aurora A, B, and C using Z-LYTE technology (Invitrogen) and ATP at Km apparent for each kinase.
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Aurora kinase A
(Homo sapiens (Human))
Xuzhou Medical College
Curated by
ChEMBL
Ligand
BDBM50241089
(2-(ethyl(3-(4-(5-(2-(3-fluorophenylamino)-2-oxoeth...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.40E+3nM
Assay Description:
Inhibition of Aurora A
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Patents
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In Depth
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Article
PubMed
Copy BDB DOI
Target
Proto-oncogene tyrosine-protein kinase receptor Ret
(Homo sapiens (Human))
Vertex Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50241089
(2-(ethyl(3-(4-(5-(2-(3-fluorophenylamino)-2-oxoeth...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 80nM
Assay Description:
Binding affinity to Ret
Checked by Author
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
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In Depth
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Article
PubMed
Copy BDB DOI
Target
Mast/stem cell growth factor receptor Kit
(Homo sapiens (Human))
Vertex Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50241089
(2-(ethyl(3-(4-(5-(2-(3-fluorophenylamino)-2-oxoeth...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 17nM
Assay Description:
Binding affinity to Kit
Checked by Author
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Platelet-derived growth factor receptor alpha
(Homo sapiens (Human))
Vertex Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50241089
(2-(ethyl(3-(4-(5-(2-(3-fluorophenylamino)-2-oxoeth...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 38nM
Assay Description:
Binding affinity to PDGFRA
Checked by Author
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
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PC sid
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In Depth
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Article
PubMed
Copy BDB DOI
Target
Platelet-derived growth factor receptor beta
(Homo sapiens (Human))
Vertex Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50241089
(2-(ethyl(3-(4-(5-(2-(3-fluorophenylamino)-2-oxoeth...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 41nM
Assay Description:
Binding affinity to PDGFRB
Checked by Author
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
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CHEMBL
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PC sid
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In Depth
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Article
PubMed
Copy BDB DOI
Target
Receptor-type tyrosine-protein kinase FLT3
(Homo sapiens (Human))
Vertex Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50241089
(2-(ethyl(3-(4-(5-(2-(3-fluorophenylamino)-2-oxoeth...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 8nM
Assay Description:
Inhibition of Flt3
Checked by Author
More data for this Ligand-Target Pair
Target Info
PDB
NCI pathway
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI