Compile Data Set for Download or QSAR
maximum 50k data

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 4 hits in this display   

TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Wuxi Pharmatech

Curated by ChEMBL
LigandPNGBDBM50302100(3-(2-(2-acetyl-2-ethylhydrazinyl)-3,4-dioxocyclobu...)
Affinity DataKi:  320nMAssay Description:Displacement of [125I]IL-8 from human CXCR2 expressed in mouse BaF3 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 1(Homo sapiens (Human))
Wuxi Pharmatech

Curated by ChEMBL
LigandPNGBDBM50302100(3-(2-(2-acetyl-2-ethylhydrazinyl)-3,4-dioxocyclobu...)
Affinity DataKi: >1.20E+4nMAssay Description:Displacement of [125I]IL-8 from human CXCR1 expressed in mouse BaF3 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Wuxi Pharmatech

Curated by ChEMBL
LigandPNGBDBM50302100(3-(2-(2-acetyl-2-ethylhydrazinyl)-3,4-dioxocyclobu...)
Affinity DataIC50:  1.25E+3nMAssay Description:Antagonist activity at CXCR2 expressed in CHO cells assessed as inhibition of IL-8-induced chemotaxisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Wuxi Pharmatech

Curated by ChEMBL
LigandPNGBDBM50302100(3-(2-(2-acetyl-2-ethylhydrazinyl)-3,4-dioxocyclobu...)
Affinity DataIC50:  3.29E+3nMAssay Description:Displacement of [125I]IL-8 from human CXCR2 expressed in mouse BaF3 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed