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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
4
hits in this display
Target
C-X-C chemokine receptor type 2
(Homo sapiens (Human))
Wuxi Pharmatech
Curated by
ChEMBL
Ligand
BDBM50302100
(3-(2-(2-acetyl-2-ethylhydrazinyl)-3,4-dioxocyclobu...)
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Affinity Data
Ki: 320nM
Assay Description:
Displacement of [125I]IL-8 from human CXCR2 expressed in mouse BaF3 cells by liquid scintillation counting
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
C-X-C chemokine receptor type 1
(Homo sapiens (Human))
Wuxi Pharmatech
Curated by
ChEMBL
Ligand
BDBM50302100
(3-(2-(2-acetyl-2-ethylhydrazinyl)-3,4-dioxocyclobu...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.20E+4nM
Assay Description:
Displacement of [125I]IL-8 from human CXCR1 expressed in mouse BaF3 cells by liquid scintillation counting
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
C-X-C chemokine receptor type 2
(Homo sapiens (Human))
Wuxi Pharmatech
Curated by
ChEMBL
Ligand
BDBM50302100
(3-(2-(2-acetyl-2-ethylhydrazinyl)-3,4-dioxocyclobu...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.25E+3nM
Assay Description:
Antagonist activity at CXCR2 expressed in CHO cells assessed as inhibition of IL-8-induced chemotaxis
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
C-X-C chemokine receptor type 2
(Homo sapiens (Human))
Wuxi Pharmatech
Curated by
ChEMBL
Ligand
BDBM50302100
(3-(2-(2-acetyl-2-ethylhydrazinyl)-3,4-dioxocyclobu...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 3.29E+3nM
Assay Description:
Displacement of [125I]IL-8 from human CXCR2 expressed in mouse BaF3 cells by liquid scintillation counting
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI