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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
3
hits in this display
Target
3-phosphoinositide-dependent protein kinase 1
(Homo sapiens (Human))
Merck Patent
US Patent
Ligand
BDBM117040
(US8664236, A20 | US9238651, A20)
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Affinity Data
IC50: 155nM
Assay Description:
The compound inhibits the target protein in the enzymatic PDK1 inhibition assay.
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
3-phosphoinositide-dependent protein kinase 1
(Homo sapiens (Human))
Merck Patent
US Patent
Ligand
BDBM117040
(US8664236, A20 | US9238651, A20)
Copy SMILES
Copy InChI
Affinity Data
IC50: 155nM
T: 2°C
Assay Description:
The experimental batches are carried out in a flashplate system with 384 wells/microtitration plate.In each case, the PDK1 sample His6-PDK1(Δ1-...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
3-phosphoinositide-dependent protein kinase 1
(Homo sapiens (Human))
Merck Patent
US Patent
Ligand
BDBM117040
(US8664236, A20 | US9238651, A20)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+4nM
pH: 8.0 T: 2°C
Assay Description:
The cellular assay for the determination of the PDK1 kinase activity is carried out as a Luminex assay in the 96-well format. PC3 cells are sown at...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI