Home
About
Info
Download
WebServices
Contact
Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
2
hits in this display
Target
Beta-secretase 1
(Homo sapiens (Human))
Vitae Pharmaceuticals
US Patent
Ligand
BDBM195086
(US10336717, Compound 135 | US9212153, 135,Ex. 100)
Copy SMILES
Copy InChI
Affinity Data
IC50: 7.30nM
Assay Description:
For each compound being tested, the BACE activity was monitored in a fluorescence quenching assay (FRET) using the ectodomain of BACE (aa 1-454) fuse...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Beta-secretase 1 [1-458]
(Homo sapiens (Human))
Vitae Pharmaceuticals
US Patent
Ligand
BDBM195086
(US10336717, Compound 135 | US9212153, 135,Ex. 100)
Copy SMILES
Copy InChI
Affinity Data
IC50: 7.30nM
pH: 4.5 T: 2°C
Assay Description:
Inhibitory activity of compounds was assessed by a fluorescence quench assay of BACE activity using commercially available substrate HiLyte Fluor 488...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI