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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
2
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Target
RAF proto-oncogene serine/threonine-protein kinase [306-648,Y340D,Y341D]
(Homo sapiens (Human))
Beigene
US Patent
Ligand
BDBM190870
(US9670203, Compound 1.73 1-(4-((4-ethylpiperazin-1...)
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Affinity Data
IC50: 840nM
T: 2°C
Assay Description:
Compounds disclosed herein were tested against B-Raf (V600E) (PV3849, from Invitrogen) or C-Raf (Y340D/Y341D) (PV3805, from Invitrogen) in a time-res...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
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Target
Serine/threonine-protein kinase B-raf [416-766,V600E]
(Homo sapiens (Human))
Beigene
US Patent
Ligand
BDBM190870
(US9670203, Compound 1.73 1-(4-((4-ethylpiperazin-1...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.30E+4nM
T: 2°C
Assay Description:
Compounds disclosed herein were tested against B-Raf (V600E) (PV3849, from Invitrogen) or C-Raf (Y340D/Y341D) (PV3805, from Invitrogen) in a time-res...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI