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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
109
hits in this display
Target
Adenosine receptor A2a/A2b
(Rattus norvegicus)
Hokkaido University
Curated by
ChEMBL
Ligand
BDBM35804
((CGS21680) 3-(4-{2-[6-Amino-9-(5-ethylcarbamoylmet...)
Copy SMILES
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Affinity Data
Ki: 8.80nM
Assay Description:
Binding affinity against adenosine A2 receptor in rat striatal membranes using [3H]NECA as radioligand
More data for this Ligand-Target Pair
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Target
Adenosine receptor A2a/A2b
(Rattus norvegicus)
Hokkaido University
Curated by
ChEMBL
Ligand
BDBM35804
((CGS21680) 3-(4-{2-[6-Amino-9-(5-ethylcarbamoylmet...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 8.80nM
Assay Description:
Inhibition of [3H]NECA binding to adenosine A2 receptor from rat striatal membranes
More data for this Ligand-Target Pair
Target Info
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Target
Adenosine receptor A2a/A2b
(Rattus norvegicus)
Hokkaido University
Curated by
ChEMBL
Ligand
BDBM35804
((CGS21680) 3-(4-{2-[6-Amino-9-(5-ethylcarbamoylmet...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 10nM
Assay Description:
Binding affinity against adenosine A2 receptor from rat striatum using [3H]NECA as radioligand.
More data for this Ligand-Target Pair
Target Info
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3D Structure (crystal)
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Target
Adenosine receptor A2a
(Rattus norvegicus (rat))
Hokkaido University
Curated by
ChEMBL
Ligand
BDBM35804
((CGS21680) 3-(4-{2-[6-Amino-9-(5-ethylcarbamoylmet...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 10nM
Assay Description:
Binding affinity against adenosine A1 receptor from rat brain membranes using [3H]cyclohexyladenosine as radioligand.
More data for this Ligand-Target Pair
Target Info
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Target
Adenosine receptor A2a
(Rattus norvegicus (rat))
Hokkaido University
Curated by
ChEMBL
Ligand
BDBM35804
((CGS21680) 3-(4-{2-[6-Amino-9-(5-ethylcarbamoylmet...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 11nM
Assay Description:
Displacement of [3H]-CGS- 21680 from adenosine A2A receptor of rat striatal tissue
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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KEGG
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3D Structure (crystal)
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Target
Adenosine receptor A2a
(Rattus norvegicus (rat))
Hokkaido University
Curated by
ChEMBL
Ligand
BDBM35804
((CGS21680) 3-(4-{2-[6-Amino-9-(5-ethylcarbamoylmet...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 11nM
Assay Description:
Binding affinity against adenosine A2a receptor from rat striatum using [3H]-CGS- 21680 as a radioligand.
More data for this Ligand-Target Pair
Target Info
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MMDB
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KEGG
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Target
Adenosine receptor A2a
(Rattus norvegicus (rat))
Hokkaido University
Curated by
ChEMBL
Ligand
BDBM35804
((CGS21680) 3-(4-{2-[6-Amino-9-(5-ethylcarbamoylmet...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 11nM
Assay Description:
Displacement of [3H]-CGS- 21680 from Adenosine A2A receptor of rat striatum
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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KEGG
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Target
Adenosine receptor A2a
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM35804
((CGS21680) 3-(4-{2-[6-Amino-9-(5-ethylcarbamoylmet...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 12nM
Assay Description:
Displacement of [3H]CGS21680 from human adenosine A2A receptor expressed in CHO cell membranes incubated for 120 mins by scintillation counting metho...
More data for this Ligand-Target Pair
Target Info
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Target
Adenosine receptor A2a
(Rattus norvegicus (rat))
Hokkaido University
Curated by
ChEMBL
Ligand
BDBM35804
((CGS21680) 3-(4-{2-[6-Amino-9-(5-ethylcarbamoylmet...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 15nM
Assay Description:
Ability to displace radioligand [3H]- CGS 21680 from adenosine A2A receptor on rat striatal membrane
More data for this Ligand-Target Pair
Target Info
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Target
Adenosine receptor A2a
(Rattus norvegicus (rat))
Hokkaido University
Curated by
ChEMBL
Ligand
BDBM35804
((CGS21680) 3-(4-{2-[6-Amino-9-(5-ethylcarbamoylmet...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 15nM
Assay Description:
Tested for the binding affinity of A2a receptor by displacing the [3H]-CGS- 21680 in rat striatal membranes
More data for this Ligand-Target Pair
Target Info
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3D Structure (crystal)
Copy BDB DOI
Target
Adenosine receptor A2a
(Rattus norvegicus (rat))
Hokkaido University
Curated by
ChEMBL
Ligand
BDBM35804
((CGS21680) 3-(4-{2-[6-Amino-9-(5-ethylcarbamoylmet...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 15nM
Assay Description:
Displacement of [3H]NECA from Adenosine A2A receptor in rat striatal membrane
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
Purchase
ChEBI
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MCE
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Article
PubMed
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Adenosine receptor A2a
(Rattus norvegicus (rat))
Hokkaido University
Curated by
ChEMBL
Ligand
BDBM35804
((CGS21680) 3-(4-{2-[6-Amino-9-(5-ethylcarbamoylmet...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 18nM
Assay Description:
Displacement of [3H]CGS21680 from adenosine A2A receptor in rat brain striatal membrane after 60 mins by liquid scintillation counting analysis
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
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ChEBI
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PubMed
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Adenosine receptor A2a
(Rattus norvegicus (rat))
Hokkaido University
Curated by
ChEMBL
Ligand
BDBM35804
((CGS21680) 3-(4-{2-[6-Amino-9-(5-ethylcarbamoylmet...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 18nM
Assay Description:
Displacement of [3H]CGS21680 from adenosine A2A receptor in rat brain striatum
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
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PubMed
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Adenosine receptor A2a
(Rattus norvegicus (rat))
Hokkaido University
Curated by
ChEMBL
Ligand
BDBM35804
((CGS21680) 3-(4-{2-[6-Amino-9-(5-ethylcarbamoylmet...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 19nM
Assay Description:
Binding affinity towards adenosine A2A receptor in rat brain striatum
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
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ChEBI
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PubMed
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Adenosine receptor A2a/A2b
(Rattus norvegicus)
Hokkaido University
Curated by
ChEMBL
Ligand
BDBM35804
((CGS21680) 3-(4-{2-[6-Amino-9-(5-ethylcarbamoylmet...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 19nM
Assay Description:
Binding to Adenosine A2 receptor was measured in ADA-pretreated rat striatal membranes using [3H]-CGS- 21680
More data for this Ligand-Target Pair
Target Info
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UniProtKB/SwissProt
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ChEBI
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PDB
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Copy BDB DOI
Target
Adenosine receptor A2a
(Rattus norvegicus (rat))
Hokkaido University
Curated by
ChEMBL
Ligand
BDBM35804
((CGS21680) 3-(4-{2-[6-Amino-9-(5-ethylcarbamoylmet...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 19nM
Assay Description:
Binding affinity to rat recombinant adenosine receptor A2a
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
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ChEBI
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PDB
3D Structure (crystal)
Copy BDB DOI
Target
Adenosine receptor A2a
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM35804
((CGS21680) 3-(4-{2-[6-Amino-9-(5-ethylcarbamoylmet...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 21nM
Assay Description:
Displacement of [3H]NECA from human recombinant adenosine A2A receptor expressed in Sf21 cells co-expressing GalphaS2, beta4, gamma2
More data for this Ligand-Target Pair
Target Info
PDB
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KEGG
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Copy BDB DOI
Target
Adenosine receptor A2a
(Rattus norvegicus (rat))
Hokkaido University
Curated by
ChEMBL
Ligand
BDBM35804
((CGS21680) 3-(4-{2-[6-Amino-9-(5-ethylcarbamoylmet...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 21.9nM
More data for this Ligand-Target Pair
Target Info
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MMDB
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KEGG
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B.MOAD
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Ligand Info
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3D Structure (crystal)
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Target
Adenosine receptor A2a
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM35804
((CGS21680) 3-(4-{2-[6-Amino-9-(5-ethylcarbamoylmet...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 27nM
Assay Description:
Binding affinity to human recombinant adenosine receptor A2a
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
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KEGG
UniProtKB/SwissProt
B.MOAD
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Copy BDB DOI
Target
Adenosine receptor A2a
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM35804
((CGS21680) 3-(4-{2-[6-Amino-9-(5-ethylcarbamoylmet...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 27nM
Assay Description:
Displacement of [3H]CGS21680 from human recombinant adenosine 2A receptor after 60 mins by gamma counting analysis
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
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ChEBI
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3D Structure (crystal)
Copy BDB DOI
Target
Adenosine receptor A2a
(Rattus norvegicus (rat))
Hokkaido University
Curated by
ChEMBL
Ligand
BDBM35804
((CGS21680) 3-(4-{2-[6-Amino-9-(5-ethylcarbamoylmet...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 27nM
Assay Description:
Displacement of [3H]CGS21680 from A2A adenosine receptor expressed in rat striatal membranes after 30 mins by liquid scintillation counting
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
Purchase
ChEBI
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MCE
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PDB
3D Structure (crystal)
Copy BDB DOI
Target
Adenosine receptor A2a
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM35804
((CGS21680) 3-(4-{2-[6-Amino-9-(5-ethylcarbamoylmet...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 27nM
Assay Description:
Binding affinity for human adenosine A2A receptor
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
MCE
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PubMed
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Adenosine receptor A2a
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM35804
((CGS21680) 3-(4-{2-[6-Amino-9-(5-ethylcarbamoylmet...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 27nM
Assay Description:
Displacement of [3H]CGS21680 from human recombinant adenosine A2A receptor expressed in HEK cells
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
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PubMed
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Adenosine receptor A2a
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM35804
((CGS21680) 3-(4-{2-[6-Amino-9-(5-ethylcarbamoylmet...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 27nM
Assay Description:
Displacement of [3H]CGS21680 from human recombinant adenosine A2A receptor
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
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MCE
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PubMed
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Adenosine receptor A2a
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM35804
((CGS21680) 3-(4-{2-[6-Amino-9-(5-ethylcarbamoylmet...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 27nM
Assay Description:
Agonist activity at human adenosine receptor A2A
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
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KEGG
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Copy BDB DOI
Target
Adenosine receptor A2a
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM35804
((CGS21680) 3-(4-{2-[6-Amino-9-(5-ethylcarbamoylmet...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 27.1nM
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
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DrugBank
antibodypedia
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Target
Adenosine receptor A2a
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM35804
((CGS21680) 3-(4-{2-[6-Amino-9-(5-ethylcarbamoylmet...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 46.2nM
Assay Description:
Displacement of [3H]CGS21680 from human recombinant adenosine A2A receptor expressed in HEK293T cells
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
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3D Structure (crystal)
Copy BDB DOI
Target
Adenosine receptor A2a
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM35804
((CGS21680) 3-(4-{2-[6-Amino-9-(5-ethylcarbamoylmet...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 46.2nM
Assay Description:
Displacement of [3H]CGS21680 from human recombinant adenosine A2A receptor expressed in HEK293T cells by scintillation counting
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
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PDB
3D Structure (crystal)
Copy BDB DOI
Target
Adenosine receptor A2a
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM35804
((CGS21680) 3-(4-{2-[6-Amino-9-(5-ethylcarbamoylmet...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 50nM
Assay Description:
Inhibition of [3H]ZM-241385 binding to human adenosine A2A receptor expressed in HeLa cells
More data for this Ligand-Target Pair
Target Info
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MMDB
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KEGG
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Target
Adenosine receptor A3
(Homo sapiens (Human))
Georgia Institute Of Technology
Curated by
ChEMBL
Ligand
BDBM35804
((CGS21680) 3-(4-{2-[6-Amino-9-(5-ethylcarbamoylmet...)
Copy SMILES
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Affinity Data
Ki: 67nM
Assay Description:
Displacement of [125I]I-AB-MECA from recombinant human adenosine A3 receptor expressed in CHO cells after 60 mins by gamma counting analysis
More data for this Ligand-Target Pair
Target Info
PDB
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Adenosine receptor A3
(Homo sapiens (Human))
Georgia Institute Of Technology
Curated by
ChEMBL
Ligand
BDBM35804
((CGS21680) 3-(4-{2-[6-Amino-9-(5-ethylcarbamoylmet...)
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Affinity Data
Ki: 67nM
Assay Description:
Displacement of [125I]AB-MECA from membranes of HEK 293 cells expressing human Adenosine A3 receptor
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Target
Adenosine receptor A3
(Homo sapiens (Human))
Georgia Institute Of Technology
Curated by
ChEMBL
Ligand
BDBM35804
((CGS21680) 3-(4-{2-[6-Amino-9-(5-ethylcarbamoylmet...)
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Affinity Data
Ki: 67nM
Assay Description:
Binding affinity to human recombinant adenosine A3 receptor
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Target
Adenosine receptor A3
(Homo sapiens (Human))
Georgia Institute Of Technology
Curated by
ChEMBL
Ligand
BDBM35804
((CGS21680) 3-(4-{2-[6-Amino-9-(5-ethylcarbamoylmet...)
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Affinity Data
Ki: 67.1nM
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Target
Adenosine receptor A3
(Homo sapiens (Human))
Georgia Institute Of Technology
Curated by
ChEMBL
Ligand
BDBM35804
((CGS21680) 3-(4-{2-[6-Amino-9-(5-ethylcarbamoylmet...)
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Affinity Data
Ki: 68nM
Assay Description:
Inhibition of [3H]NECA binding to human adenosine A3 receptor expressed in HeLa cells
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Target
Adenosine receptor A2a
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM35804
((CGS21680) 3-(4-{2-[6-Amino-9-(5-ethylcarbamoylmet...)
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Affinity Data
Ki: 70nM
Assay Description:
Displacement of [3H]2-[p-(2-carboxyethyl)phenyl-ethylamino]-5'-N-ethylcarboxamidoadenosine from human adenosine A2a receptor expressed in HEK293 cell...
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Copy BDB DOI
Target
Adenosine receptor A2a
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM35804
((CGS21680) 3-(4-{2-[6-Amino-9-(5-ethylcarbamoylmet...)
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Affinity Data
Ki: 70nM
Assay Description:
Displacement of [3H]2-[p-(2-carboxyethyl)phenylethylamino]-5'-N-ethylcarboxamido-adenosine from human A2A adenosine receptor expressed in HEK293 cell...
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Target
Adenosine receptor A3
(Homo sapiens (Human))
Georgia Institute Of Technology
Curated by
ChEMBL
Ligand
BDBM35804
((CGS21680) 3-(4-{2-[6-Amino-9-(5-ethylcarbamoylmet...)
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Affinity Data
Ki: 114nM
Assay Description:
Displacement of [125I]I-AB-MECA from human recombinant adenosine A3 receptor expressed in CHO cells after 60 mins by gamma counting analysis
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Target
Adenosine receptor A3
(Homo sapiens (Human))
Georgia Institute Of Technology
Curated by
ChEMBL
Ligand
BDBM35804
((CGS21680) 3-(4-{2-[6-Amino-9-(5-ethylcarbamoylmet...)
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Affinity Data
Ki: 114nM
Assay Description:
Displacement of [125I]-AB-MECA from human recombinant adenosine A3 receptor
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Target
Adenosine receptor A1
(Homo sapiens (Human))
TBA
Curated by
ChEMBL
Ligand
BDBM35804
((CGS21680) 3-(4-{2-[6-Amino-9-(5-ethylcarbamoylmet...)
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Affinity Data
Ki: 289nM
Assay Description:
Displacement of [3H]CCPA from human recombinant adenosine A1 receptor
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Copy BDB DOI
Target
Adenosine receptor A1
(Homo sapiens (Human))
TBA
Curated by
ChEMBL
Ligand
BDBM35804
((CGS21680) 3-(4-{2-[6-Amino-9-(5-ethylcarbamoylmet...)
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Affinity Data
Ki: 289nM
Assay Description:
Displacement of [3H]CCPA from human recombinant adenosine A1 receptor
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Copy BDB DOI
Target
Adenosine receptor A1
(Homo sapiens (Human))
TBA
Curated by
ChEMBL
Ligand
BDBM35804
((CGS21680) 3-(4-{2-[6-Amino-9-(5-ethylcarbamoylmet...)
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Affinity Data
Ki: 289nM
Assay Description:
Binding affinity for human adenosine A1 receptor
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Copy BDB DOI
Target
Adenosine receptor A1
(Homo sapiens (Human))
TBA
Curated by
ChEMBL
Ligand
BDBM35804
((CGS21680) 3-(4-{2-[6-Amino-9-(5-ethylcarbamoylmet...)
Copy SMILES
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Affinity Data
Ki: 290nM
Assay Description:
Binding affinity to human recombinant adenosine A1 receptor
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Copy BDB DOI
Target
Adenosine receptor A1
(Homo sapiens (Human))
TBA
Curated by
ChEMBL
Ligand
BDBM35804
((CGS21680) 3-(4-{2-[6-Amino-9-(5-ethylcarbamoylmet...)
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Affinity Data
Ki: 290nM
Assay Description:
Agonist activity at human adenosine receptor A1
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Target
Adenosine receptor A1
(Homo sapiens (Human))
TBA
Curated by
ChEMBL
Ligand
BDBM35804
((CGS21680) 3-(4-{2-[6-Amino-9-(5-ethylcarbamoylmet...)
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Affinity Data
Ki: 302nM
Assay Description:
Inhibition of [3H]DPCPX binding to human adenosine A1 receptor expressed in CHO cells
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Adenosine receptor A1
(Rattus norvegicus (rat))
Zeneca Pharmaceuticals
Curated by
PDSP K
i
Database
Ligand
BDBM35804
((CGS21680) 3-(4-{2-[6-Amino-9-(5-ethylcarbamoylmet...)
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Affinity Data
Ki: 335nM
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Target
Adenosine receptor A1
(Homo sapiens (Human))
TBA
Curated by
ChEMBL
Ligand
BDBM35804
((CGS21680) 3-(4-{2-[6-Amino-9-(5-ethylcarbamoylmet...)
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Affinity Data
Ki: 380nM
Assay Description:
Displacement of [3H]N6-phenylisopropyladenosine from human A1 adenosine receptor expressed in CHO cell membranes after 60 mins
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Target
Adenosine receptor A1
(Homo sapiens (Human))
TBA
Curated by
ChEMBL
Ligand
BDBM35804
((CGS21680) 3-(4-{2-[6-Amino-9-(5-ethylcarbamoylmet...)
Copy SMILES
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Affinity Data
Ki: 380nM
Assay Description:
Displacement of [3H]R-PIA from human adenosine A1 receptor expressed in CHO cells
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Target
Adenosine receptor A3
(Homo sapiens (Human))
Georgia Institute Of Technology
Curated by
ChEMBL
Ligand
BDBM35804
((CGS21680) 3-(4-{2-[6-Amino-9-(5-ethylcarbamoylmet...)
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Affinity Data
Ki: 384nM
Assay Description:
Displacement of [3H]AB-MECA from human adenosine A3 receptor expressed in CHO cell membranes incubated for 30 mins by scintillation counting method
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Target
Adenosine receptor A2a
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM35804
((CGS21680) 3-(4-{2-[6-Amino-9-(5-ethylcarbamoylmet...)
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Affinity Data
Ki: 503nM
Assay Description:
Displacement of [3H]-ZM24135 from human adenosine A2A receptor expressed in HEK293 cells after 1 hr by scintillation counting
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Target
Adenosine receptor A1
(Rattus norvegicus (rat))
Zeneca Pharmaceuticals
Curated by
PDSP K
i
Database
Ligand
BDBM35804
((CGS21680) 3-(4-{2-[6-Amino-9-(5-ethylcarbamoylmet...)
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Affinity Data
Ki: 569nM
Assay Description:
Binding affinity against adenosine A1 receptor from rat brain using [3H]CHA as a radioligand.
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Target
Adenosine receptor A1
(Rattus norvegicus (rat))
Zeneca Pharmaceuticals
Curated by
PDSP K
i
Database
Ligand
BDBM35804
((CGS21680) 3-(4-{2-[6-Amino-9-(5-ethylcarbamoylmet...)
Copy SMILES
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Affinity Data
Ki: 569nM
Assay Description:
Displacement of [3H]CHA from Adenosine A1 receptor of rat brain
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Target
Adenosine receptor A3
(Homo sapiens (Human))
Georgia Institute Of Technology
Curated by
ChEMBL
Ligand
BDBM35804
((CGS21680) 3-(4-{2-[6-Amino-9-(5-ethylcarbamoylmet...)
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Affinity Data
Ki: 570nM
Assay Description:
Displacement of [125I]N6-(4-amino-3-iodobenzyl)adenosine-5'-N-methyluronamide from human A3 adenosine receptor expressed in CHO cell membranes after ...
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Target
Adenosine receptor A3
(Homo sapiens (Human))
Georgia Institute Of Technology
Curated by
ChEMBL
Ligand
BDBM35804
((CGS21680) 3-(4-{2-[6-Amino-9-(5-ethylcarbamoylmet...)
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Affinity Data
Ki: 570nM
Assay Description:
Displacement of [125I]I-AB-MECA from human adenosine A3 receptor expressed in CHO cells
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Target
Adenosine receptor A3
(Rattus norvegicus)
Leiden University
Curated by
ChEMBL
Ligand
BDBM35804
((CGS21680) 3-(4-{2-[6-Amino-9-(5-ethylcarbamoylmet...)
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Affinity Data
Ki: 584nM
Assay Description:
Binding affinity for rat adenosine A3 receptor
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Target
Adenosine receptor A3
(Rattus norvegicus)
Leiden University
Curated by
ChEMBL
Ligand
BDBM35804
((CGS21680) 3-(4-{2-[6-Amino-9-(5-ethylcarbamoylmet...)
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Affinity Data
Ki: 584nM
Assay Description:
Tested for the binding affinity of A3 receptor by displacing N6-[[125I]-4-amino-3-iodobenzyl]-adenosine-5''-N-methyluronamide from membranes of CHO ...
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Target
Adenosine receptor A3
(Homo sapiens (Human))
Georgia Institute Of Technology
Curated by
ChEMBL
Ligand
BDBM35804
((CGS21680) 3-(4-{2-[6-Amino-9-(5-ethylcarbamoylmet...)
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Affinity Data
Ki: 584nM
Assay Description:
Displacement of [125I]APNEA from human Adenosine A3 receptor expressed in HEK 293 cells
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Target
Adenosine receptor A3
(Homo sapiens (Human))
Georgia Institute Of Technology
Curated by
ChEMBL
Ligand
BDBM35804
((CGS21680) 3-(4-{2-[6-Amino-9-(5-ethylcarbamoylmet...)
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Affinity Data
Ki: 980nM
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Target
Adenosine receptor A1
(Rattus norvegicus (rat))
Zeneca Pharmaceuticals
Curated by
PDSP K
i
Database
Ligand
BDBM35804
((CGS21680) 3-(4-{2-[6-Amino-9-(5-ethylcarbamoylmet...)
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Affinity Data
Ki: 1.14E+3nM
Assay Description:
Binding affinity against adenosine A1 receptor from rat brain membranes using [3H]cyclohexyladenosine as radioligand.
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Target
Adenosine receptor A1
(Rattus norvegicus (rat))
Zeneca Pharmaceuticals
Curated by
PDSP K
i
Database
Ligand
BDBM35804
((CGS21680) 3-(4-{2-[6-Amino-9-(5-ethylcarbamoylmet...)
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Affinity Data
Ki: 1.23E+3nM
Assay Description:
Inhibition of [3H]CHA binding to adenosine A1 receptor from rat brain membranes
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Target
Adenosine receptor A1
(Rattus norvegicus (rat))
Zeneca Pharmaceuticals
Curated by
PDSP K
i
Database
Ligand
BDBM35804
((CGS21680) 3-(4-{2-[6-Amino-9-(5-ethylcarbamoylmet...)
Copy SMILES
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Affinity Data
Ki: 1.23E+3nM
Assay Description:
Binding affinity against adenosine A1 receptor in rat brain membranes using [3H]CHA as radioligand
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Target
Adenosine receptor A1
(Rattus norvegicus (rat))
Zeneca Pharmaceuticals
Curated by
PDSP K
i
Database
Ligand
BDBM35804
((CGS21680) 3-(4-{2-[6-Amino-9-(5-ethylcarbamoylmet...)
Copy SMILES
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Affinity Data
Ki: 1.41E+3nM
Assay Description:
Adenosine A1 receptor binding was measured in adenosine deaminase (ADA) pretreated rat cortical membranes using [3H]cyclohexyladenosine in the presen...
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Target
Adenosine receptor A1
(Rattus norvegicus (rat))
Zeneca Pharmaceuticals
Curated by
PDSP K
i
Database
Ligand
BDBM35804
((CGS21680) 3-(4-{2-[6-Amino-9-(5-ethylcarbamoylmet...)
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Affinity Data
Ki: 1.80E+3nM
Assay Description:
Displacement of [3H]CCPA from adenosine A1 receptor in rat brain cortex
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Target
Adenosine receptor A1
(Rattus norvegicus (rat))
Zeneca Pharmaceuticals
Curated by
PDSP K
i
Database
Ligand
BDBM35804
((CGS21680) 3-(4-{2-[6-Amino-9-(5-ethylcarbamoylmet...)
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Affinity Data
Ki: 1.80E+3nM
Assay Description:
Displacement of [3H]CCPA from adenosine A1 receptor in rat brain cortical membrane after 90 mins by liquid scintillation counting analysis
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Adenosine receptor A1
(Rattus norvegicus (rat))
Zeneca Pharmaceuticals
Curated by
PDSP K
i
Database
Ligand
BDBM35804
((CGS21680) 3-(4-{2-[6-Amino-9-(5-ethylcarbamoylmet...)
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Affinity Data
Ki: 1.80E+3nM
Assay Description:
Binding affinity towards adenosine A1 receptor in rat brain cortex
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Adenosine receptor A1
(Rattus norvegicus (rat))
Zeneca Pharmaceuticals
Curated by
PDSP K
i
Database
Ligand
BDBM35804
((CGS21680) 3-(4-{2-[6-Amino-9-(5-ethylcarbamoylmet...)
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Affinity Data
Ki: 2.60E+3nM
Assay Description:
Displacement of [3H]- DPCPX from adenosine A1 receptor on rat cortical membrane
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Adenosine receptor A1
(Rattus norvegicus (rat))
Zeneca Pharmaceuticals
Curated by
PDSP K
i
Database
Ligand
BDBM35804
((CGS21680) 3-(4-{2-[6-Amino-9-(5-ethylcarbamoylmet...)
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Affinity Data
Ki: 2.60E+3nM
Assay Description:
Inhibition of [3H]PIA binding to rat cortical adenosine A1 receptor
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Target
Adenosine receptor A1
(Rattus norvegicus (rat))
Zeneca Pharmaceuticals
Curated by
PDSP K
i
Database
Ligand
BDBM35804
((CGS21680) 3-(4-{2-[6-Amino-9-(5-ethylcarbamoylmet...)
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Affinity Data
Ki: 2.60E+3nM
Assay Description:
Tested for the binding affinity of A1 receptor by displacing the [3H]-PIA in rat brain membranes
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Target
Adenosine receptor A1
(Rattus norvegicus (rat))
Zeneca Pharmaceuticals
Curated by
PDSP K
i
Database
Ligand
BDBM35804
((CGS21680) 3-(4-{2-[6-Amino-9-(5-ethylcarbamoylmet...)
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Affinity Data
Ki: 2.60E+3nM
Assay Description:
Displacement of [3H]CHA from Adenosine A1 receptor in rat cortical membrane
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Adenosine receptor A1
(Rattus norvegicus (rat))
Zeneca Pharmaceuticals
Curated by
PDSP K
i
Database
Ligand
BDBM35804
((CGS21680) 3-(4-{2-[6-Amino-9-(5-ethylcarbamoylmet...)
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Affinity Data
Ki: 2.60E+3nM
Assay Description:
Binding affinity against adenosine A1 receptor using [3H]-CHA or [3H]PIA as radioligand
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Adenosine receptor A1
(Rattus norvegicus (rat))
Zeneca Pharmaceuticals
Curated by
PDSP K
i
Database
Ligand
BDBM35804
((CGS21680) 3-(4-{2-[6-Amino-9-(5-ethylcarbamoylmet...)
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Affinity Data
Ki: 3.08E+3nM
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Adenosine receptor A1
(Rattus norvegicus (rat))
Zeneca Pharmaceuticals
Curated by
PDSP K
i
Database
Ligand
BDBM35804
((CGS21680) 3-(4-{2-[6-Amino-9-(5-ethylcarbamoylmet...)
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Affinity Data
Ki: 9.90E+3nM
Assay Description:
Displacement of [3H]-R-PIA from adenosine A1 receptor of Wistar rat forebrain
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Adenosine receptor A2b
(Homo sapiens (Human))
University Of Virginia
Curated by
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i
Database
Ligand
BDBM35804
((CGS21680) 3-(4-{2-[6-Amino-9-(5-ethylcarbamoylmet...)
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Affinity Data
Ki: >1.00E+4nM
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Target
Adenosine receptor A1
(Homo sapiens (Human))
TBA
Curated by
ChEMBL
Ligand
BDBM35804
((CGS21680) 3-(4-{2-[6-Amino-9-(5-ethylcarbamoylmet...)
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Affinity Data
Ki: >1.00E+4nM
Assay Description:
Displacement of [3H]CCPA from human adenosine A1 receptor expressed in CHO cell membranes incubated for 120 mins by scintillation counting method
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Adenosine receptor A3
(Homo sapiens (Human))
Georgia Institute Of Technology
Curated by
ChEMBL
Ligand
BDBM35804
((CGS21680) 3-(4-{2-[6-Amino-9-(5-ethylcarbamoylmet...)
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Affinity Data
Ki: >1.00E+4nM
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Target
Adenosine receptor A2b
(Homo sapiens (Human))
University Of Virginia
Curated by
PDSP K
i
Database
Ligand
BDBM35804
((CGS21680) 3-(4-{2-[6-Amino-9-(5-ethylcarbamoylmet...)
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Affinity Data
Ki: >1.00E+4nM
Assay Description:
Displacement of [3H]PSB-603 from human recombinant adenosine A2B receptor expressed in CHO cells after 75 mins by liquid scintillation assay
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Adenosine receptor A1
(Rattus norvegicus (rat))
Zeneca Pharmaceuticals
Curated by
PDSP K
i
Database
Ligand
BDBM35804
((CGS21680) 3-(4-{2-[6-Amino-9-(5-ethylcarbamoylmet...)
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Affinity Data
Ki: >1.00E+4nM
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Target
Adenosine receptor A2b
(Homo sapiens (Human))
University Of Virginia
Curated by
PDSP K
i
Database
Ligand
BDBM35804
((CGS21680) 3-(4-{2-[6-Amino-9-(5-ethylcarbamoylmet...)
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Affinity Data
Ki: >1.00E+4nM
Assay Description:
Inhibition of [3H]DPCPX binding to human adenosine A2B receptor expressed in HEK293 cells
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Target
Adenosine receptor A2a
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM35804
((CGS21680) 3-(4-{2-[6-Amino-9-(5-ethylcarbamoylmet...)
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Affinity Data
IC50: 19nM
Assay Description:
Agonist activity at adenosine A2A receptor in human neutrophils assessed as inhibition of fMLP-induced reactive oxygen species release by chemilumine...
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Target
Adenosine receptor A2a
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM35804
((CGS21680) 3-(4-{2-[6-Amino-9-(5-ethylcarbamoylmet...)
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Affinity Data
EC50: 1.40nM
Assay Description:
Partial agonist activity at human A2A receptor expressed in HEK293 cell membranes assessed as intrinsic activity by measuring cell index change withi...
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Target
Adenosine receptor A1
(Rattus norvegicus (rat))
Zeneca Pharmaceuticals
Curated by
PDSP K
i
Database
Ligand
BDBM35804
((CGS21680) 3-(4-{2-[6-Amino-9-(5-ethylcarbamoylmet...)
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Affinity Data
EC50: >1.00E+4nM
Assay Description:
Activitty at Adenosine A1 receptor of rat atria
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Target
Adenosine receptor A2a
(Homo sapiens (Human))
Universit£
Curated by
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Ligand
BDBM35804
((CGS21680) 3-(4-{2-[6-Amino-9-(5-ethylcarbamoylmet...)
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Affinity Data
Kd: 7.60nM
Assay Description:
Kd in saturation experiments using [3H]CGS-21680 at H250N mutant receptor in COS-7 cells
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Target
Adenosine receptor A2a
(Homo sapiens (Human))
Universit£
Curated by
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Ligand
BDBM35804
((CGS21680) 3-(4-{2-[6-Amino-9-(5-ethylcarbamoylmet...)
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Affinity Data
Kd: 27nM
Assay Description:
Kd in saturation experiments using [3H]CGS-21680 at V84L mutant receptor in COS-7 cells
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Target
Adenosine receptor A2a
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM35804
((CGS21680) 3-(4-{2-[6-Amino-9-(5-ethylcarbamoylmet...)
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Affinity Data
Kd: 7.60nM
pH: 6.8
Assay Description:
Saturation binding of human Adenosine A2A receptor (H250N) at pH 6.8
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Target
Adenosine receptor A2a
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM35804
((CGS21680) 3-(4-{2-[6-Amino-9-(5-ethylcarbamoylmet...)
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Affinity Data
Kd: 74nM
pH: 7.5
Assay Description:
Saturation binding characteristics of wild type human Adenosine A2A receptor at pH 7.5
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Adenosine receptor A2a
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM35804
((CGS21680) 3-(4-{2-[6-Amino-9-(5-ethylcarbamoylmet...)
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Affinity Data
Kd: 4.30nM
pH: 5.5
Assay Description:
Saturation binding of mutant human Adenosine A2A receptor (H250N) at pH 5.5
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Target
Adenosine receptor A2a
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM35804
((CGS21680) 3-(4-{2-[6-Amino-9-(5-ethylcarbamoylmet...)
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Affinity Data
Kd: 12nM
pH: 7.5
Assay Description:
Saturation binding of human Adenosine A2A receptor H250N at pH 7.5
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Target
Adenosine receptor A2a
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM35804
((CGS21680) 3-(4-{2-[6-Amino-9-(5-ethylcarbamoylmet...)
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Affinity Data
Kd: 99nM
pH: 8.4
Assay Description:
Saturation binding of human Adenosine A2A receptor H250N at pH 8.4
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Target
Adenosine receptor A2a
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM35804
((CGS21680) 3-(4-{2-[6-Amino-9-(5-ethylcarbamoylmet...)
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Affinity Data
Kd: 36nM
pH: 6.8
Assay Description:
Saturation binding of wild type human Adenosine A2A receptor at pH 6.8
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Target
Adenosine receptor A2a
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM35804
((CGS21680) 3-(4-{2-[6-Amino-9-(5-ethylcarbamoylmet...)
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Affinity Data
Kd: 22nM
pH: 5.5
Assay Description:
Saturation binding characteristics of wild type human Adenosine A2A receptor at pH 5.5
More data for this Ligand-Target Pair
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Target
Adenosine receptor A2a
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM35804
((CGS21680) 3-(4-{2-[6-Amino-9-(5-ethylcarbamoylmet...)
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Affinity Data
Kd: 36nM
Assay Description:
Kd in saturation experiments using [3H]CGS-21680 at WT receptor in COS-7 cells
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Target
Adenosine receptor A2b
(Homo sapiens (Human))
University Of Virginia
Curated by
PDSP K
i
Database
Ligand
BDBM35804
((CGS21680) 3-(4-{2-[6-Amino-9-(5-ethylcarbamoylmet...)
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Affinity Data
EC50: 3.61E+5nM
Assay Description:
Agonist activity at human recombinant adenosine receptor A2b by cAMP assay
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Target
Adenosine receptor A2a
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM35804
((CGS21680) 3-(4-{2-[6-Amino-9-(5-ethylcarbamoylmet...)
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Affinity Data
EC50: 2.10nM
Assay Description:
Agonist activity at human adenosine A2a receptor expressed in CHO cells assessed as stimulation of cAMP formation after 24 hrs
More data for this Ligand-Target Pair
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Target
Adenosine receptor A2a
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM35804
((CGS21680) 3-(4-{2-[6-Amino-9-(5-ethylcarbamoylmet...)
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Affinity Data
Kd: 4.40nM
Assay Description:
Displacement of [3H]4-[2-[7-amino-2-(2-furyl)-1,2,4-triazolo[1,5-a][1,3,5]triazin-5-yl-amino]ethylphenol from wild type human adenosine A2a receptor ...
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Target
Adenosine receptor A2a
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM35804
((CGS21680) 3-(4-{2-[6-Amino-9-(5-ethylcarbamoylmet...)
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Affinity Data
EC50: 18nM
Assay Description:
Agonist activity at human adenosine A2A receptor expressed in CHO cells assessed as stimulation of [3H]cAMP levels by scintillation counting method
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Target
Adenosine receptor A2b
(Homo sapiens (Human))
University Of Virginia
Curated by
PDSP K
i
Database
Ligand
BDBM35804
((CGS21680) 3-(4-{2-[6-Amino-9-(5-ethylcarbamoylmet...)
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Affinity Data
EC50: >1.00E+4nM
Assay Description:
Agonist activity at human adenosine A2B receptor expressed in CHO cells assessed as stimulation of [3H]cAMP levels by scintillation counting method
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Target
Adenosine receptor A1
(Homo sapiens (Human))
TBA
Curated by
ChEMBL
Ligand
BDBM35804
((CGS21680) 3-(4-{2-[6-Amino-9-(5-ethylcarbamoylmet...)
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Affinity Data
EC50: 6.31E+5nM
Assay Description:
Agonist activity at human Adenosine A1 receptor expressed in yeast cells coexpressed with chimeric GPA1/Galphai1 after 16 hrs by beta galactosidase r...
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Target
Adenosine receptor A2a
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM35804
((CGS21680) 3-(4-{2-[6-Amino-9-(5-ethylcarbamoylmet...)
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Affinity Data
EC50: 2.00E+4nM
Assay Description:
Agonist activity at human Adenosine A2A receptor expressed in yeast cells coexpressed with chimeric GPA1/Galphas after 16 hrs by beta-galactosidase r...
More data for this Ligand-Target Pair
Target Info
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Target
Adenosine receptor A2b
(Homo sapiens (Human))
University Of Virginia
Curated by
PDSP K
i
Database
Ligand
BDBM35804
((CGS21680) 3-(4-{2-[6-Amino-9-(5-ethylcarbamoylmet...)
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Affinity Data
EC50: 6.31E+6nM
Assay Description:
Agonist activity at human Adenosine A2B receptor expressed in yeast cells coexpressed with chimeric GPA1/Galphas after 16 hrs by beta-galactosidase r...
More data for this Ligand-Target Pair
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Target
Adenosine receptor A1
(Homo sapiens (Human))
TBA
Curated by
ChEMBL
Ligand
BDBM35804
((CGS21680) 3-(4-{2-[6-Amino-9-(5-ethylcarbamoylmet...)
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Affinity Data
EC50: >1.00E+4nM
Assay Description:
Agonist activity at human adenosine A1 receptor expressed in CHO cells by GTPPgammaS binding assay
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Target
Adenosine receptor A3
(Homo sapiens (Human))
Georgia Institute Of Technology
Curated by
ChEMBL
Ligand
BDBM35804
((CGS21680) 3-(4-{2-[6-Amino-9-(5-ethylcarbamoylmet...)
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Affinity Data
EC50: 613nM
Assay Description:
Agonist activity at human adenosine A3 receptor expressed in CHO cells by GTPPgammaS binding assay
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Target
Adenosine receptor A2b
(Homo sapiens (Human))
University Of Virginia
Curated by
PDSP K
i
Database
Ligand
BDBM35804
((CGS21680) 3-(4-{2-[6-Amino-9-(5-ethylcarbamoylmet...)
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Affinity Data
EC50: >1.00E+4nM
Assay Description:
Agonist activity at human adenosine A2B receptor expressed in CHO cells assessed as effect on cAMP production by luciferase reporter gene assay
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Target
Adenosine receptor A1
(Homo sapiens (Human))
TBA
Curated by
ChEMBL
Ligand
BDBM35804
((CGS21680) 3-(4-{2-[6-Amino-9-(5-ethylcarbamoylmet...)
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Affinity Data
EC50: 6.44E+3nM
Assay Description:
Binding against human adenosine A1 receptor
More data for this Ligand-Target Pair
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Target
Adenosine receptor A1
(Rattus norvegicus (rat))
Zeneca Pharmaceuticals
Curated by
PDSP K
i
Database
Ligand
BDBM35804
((CGS21680) 3-(4-{2-[6-Amino-9-(5-ethylcarbamoylmet...)
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Affinity Data
EC50: >100nM
Assay Description:
[S]GTP gamma-S binding against adenosine A1 receptor in rat brain
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Target
Adenosine receptor A1
(GUINEA PIG)
University Of South Florida
Curated by
ChEMBL
Ligand
BDBM35804
((CGS21680) 3-(4-{2-[6-Amino-9-(5-ethylcarbamoylmet...)
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Affinity Data
EC50: 2.46E+4nM
Assay Description:
Prolongation of the stimulus-QRS interval by 50% of the maximum response at the Adenosine A1 receptor in langendorff guinea pig heart preparation
Checked by Author
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Target
Adenosine receptor A2a
(Rattus norvegicus (rat))
Hokkaido University
Curated by
ChEMBL
Ligand
BDBM35804
((CGS21680) 3-(4-{2-[6-Amino-9-(5-ethylcarbamoylmet...)
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Affinity Data
EC50: 115nM
Assay Description:
Functional activity against adenosine A2a receptor from rat aorta.
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Target
Adenosine receptor A2a
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM35804
((CGS21680) 3-(4-{2-[6-Amino-9-(5-ethylcarbamoylmet...)
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Affinity Data
Kd: 632nM
pH: 8.4
Assay Description:
Saturation binding of wild type human Adenosine A2A receptor at pH 8.4
More data for this Ligand-Target Pair
Target Info
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Target
Adenosine receptor A2b
(Homo sapiens (Human))
University Of Virginia
Curated by
PDSP K
i
Database
Ligand
BDBM35804
((CGS21680) 3-(4-{2-[6-Amino-9-(5-ethylcarbamoylmet...)
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Affinity Data
EC50: 2.13E+5nM
Assay Description:
Effective concentration for cAMP production in CHO-KI cells stably transfected with human adenosine A2B receptor cDNA
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Target
Adenosine receptor A1
(Rattus norvegicus (rat))
Zeneca Pharmaceuticals
Curated by
PDSP K
i
Database
Ligand
BDBM35804
((CGS21680) 3-(4-{2-[6-Amino-9-(5-ethylcarbamoylmet...)
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Affinity Data
EC50: >1.00E+4nM
Assay Description:
Functional activity against adenosine A1 receptor from rat atria.
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Copy BDB DOI
Target
Adenosine receptor A2a
(Rattus norvegicus (rat))
Hokkaido University
Curated by
ChEMBL
Ligand
BDBM35804
((CGS21680) 3-(4-{2-[6-Amino-9-(5-ethylcarbamoylmet...)
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Affinity Data
EC50: 115nM
Assay Description:
Functional activity at Adenosine A2A receptor as vasorelaation of rat aorta
More data for this Ligand-Target Pair
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