Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)
Found 14 hits in this display
IC50: >1.00E+4nMAssay Description:Antagonist activity at human FXR assessed as ligand dependent binding of cofactor to the receptor-ligand complex by TRF methodMore data for this Ligand-Target Pair
EC50: 75nMAssay Description:Agonist activity at human TGR5 receptor in CHO cells assessed as elevation of cAMP level by uninduced cAMP detection method in absence of doxycyclineMore data for this Ligand-Target Pair
EC50: 147nMAssay Description:Agonist activity at human recombinant TGR5 expressed in NCI-H716 cells assessed as increase in intracellular cAMP measured after 1 hrMore data for this Ligand-Target Pair
EC50: 110nMAssay Description:Agonist activity at human TGR5 in human PBMC cells assessed as increase in intracellular cAMP measured after 1 hr by human whole blood assayMore data for this Ligand-Target Pair