Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetAdenosine receptor A1(Rattus norvegicus (rat))
Pfizer

Curated by ChEMBL

LigandBDBM50015766(CHEMBL74681 | Ethyl-(1-ethyl-8-methoxy-[1,2,4]tria...)Copy SMILESCopy InChI

Affinity DataIC50:  710nMAssay Description:Binding affinity towards the adenosine A1 receptor in cerebral cortices of Sprague-Dawley male rats using [3H]CHA as radioligand.More data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
Pfizer

Curated by ChEMBL

LigandBDBM50015766(CHEMBL74681 | Ethyl-(1-ethyl-8-methoxy-[1,2,4]tria...)Copy SMILESCopy InChI

Affinity DataIC50:  4.50E+3nMAssay Description:Evaluated for the binding affinity towards the Adenosine A2 receptor in corpora striata of rats using [3H]NECA as radioligand.More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI