Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 4 hits in this display   

TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL

LigandBDBM50105763(CHEMBL420081 | D3RKN_10 | Ethyl-{4-[5-(4-fluoro-ph...)Copy SMILESCopy InChI

Affinity DataIC50:  9.60nMAssay Description:Inhibition against Mitogen-activated protein kinase p38 alphaMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
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TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
D3R/Abbott

LigandBDBM50105763(CHEMBL420081 | D3RKN_10 | Ethyl-{4-[5-(4-fluoro-ph...)Copy SMILESCopy InChI

Affinity DataKd:  4.10E+3nMAssay Description:D3R2022More data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails PubMed
Copy BDB DOI

TargetAngiopoietin-1 receptor(Homo sapiens (Human))
D3R/Abbott

LigandBDBM50105763(CHEMBL420081 | D3RKN_10 | Ethyl-{4-[5-(4-fluoro-ph...)Copy SMILESCopy InChI

Affinity DataKd:  1.00E+4nMAssay Description:D3R2025More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails PubMed
Copy BDB DOI

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
D3R/Abbott

LigandBDBM50105763(CHEMBL420081 | D3RKN_10 | Ethyl-{4-[5-(4-fluoro-ph...)Copy SMILESCopy InChI

Affinity DataKd:  1.00E+4nMAssay Description:D3R2021More data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails PubMed
Copy BDB DOI