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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 5 hits in this display   

TargetKappa-type opioid receptor(Homo sapiens (Human))
Mclean Hospital

Curated by ChEMBL
LigandPNGBDBM50266420((2S,4aR,6aR,7R,9S,10aS,10bR)-2-ethyl 7-methyl 9-ac...)
Affinity DataKi:  196nMAssay Description:Displacement of [3H]diprenorphine from human KOPR expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Mclean Hospital

Curated by ChEMBL
LigandPNGBDBM50266420((2S,4aR,6aR,7R,9S,10aS,10bR)-2-ethyl 7-methyl 9-ac...)
Affinity DataKi:  196nMAssay Description:In vitro binding assay: The affinities of compounds for opioid receptors were determined by competitive inhibition of [3H]diprenorphine binding to ka...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Mclean Hospital

Curated by ChEMBL
LigandPNGBDBM50266420((2S,4aR,6aR,7R,9S,10aS,10bR)-2-ethyl 7-methyl 9-ac...)
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity to rat MOPR expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
Mclean Hospital

Curated by ChEMBL
LigandPNGBDBM50266420((2S,4aR,6aR,7R,9S,10aS,10bR)-2-ethyl 7-methyl 9-ac...)
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity to mouse DOPR expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Mclean Hospital

Curated by ChEMBL
LigandPNGBDBM50266420((2S,4aR,6aR,7R,9S,10aS,10bR)-2-ethyl 7-methyl 9-ac...)
Affinity DataEC50:  508nMAssay Description:Agonist activity at human KOPR expressed in CHO cells assessed as enhancenment of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed