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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
9
hits in this display
Target
Angiotensin-converting enzyme
(Homo sapiens (Human))
TBA
Curated by
ChEMBL
Ligand
BDBM50368166
(Accupril | QUINAPRIL)
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Affinity Data
IC50: 8.30nM
Assay Description:
In vitro inhibitory activity against Angiotensin I converting enzyme from unpurified guinea pig serum
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
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ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
DrugBank
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Target
Angiotensin-converting enzyme
(Homo sapiens (Human))
TBA
Curated by
ChEMBL
Ligand
BDBM50368166
(Accupril | QUINAPRIL)
Copy SMILES
Copy InChI
Affinity Data
IC50: 8.30nM
Assay Description:
Inhibition of guinea pig angiotensin I converting enzyme
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
Angiotensin-converting enzyme
(Homo sapiens (Human))
TBA
Curated by
ChEMBL
Ligand
BDBM50368166
(Accupril | QUINAPRIL)
Copy SMILES
Copy InChI
Affinity Data
IC50: 8.30nM
Assay Description:
Inhibitory activity against angiotensin I converting enzyme (ACE)
Checked by Author
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
Angiotensin-converting enzyme
(Homo sapiens (Human))
TBA
Curated by
ChEMBL
Ligand
BDBM50368166
(Accupril | QUINAPRIL)
Copy SMILES
Copy InChI
Affinity Data
IC50: 8.30nM
Assay Description:
Compound was tested for its inhibitory potency against angiotensin I converting enzyme.
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
Angiotensin-converting enzyme
(Oryctolagus cuniculus)
Csir-Indian Institute Of Chemical Technology
Curated by
ChEMBL
Ligand
BDBM50368166
(Accupril | QUINAPRIL)
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Copy InChI
Affinity Data
IC50: 110nM
Assay Description:
Inhibition of rabbit lung ACE assessed as hippuryl-histidyl-leucine hydrolysis after 30 mins by colorimetric method
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Bile salt export pump
(Homo sapiens (Human))
Astrazeneca
Curated by
ChEMBL
Ligand
BDBM50368166
(Accupril | QUINAPRIL)
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Affinity Data
IC50: 1.55E+4nM
Assay Description:
Inhibition of human BSEP expressed in baculovirus transfected fall armyworm Sf21 cell membranes vesicles assessed as reduction in ATP-dependent [3H]-...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Bile salt export pump
(Homo sapiens (Human))
Astrazeneca
Curated by
ChEMBL
Ligand
BDBM50368166
(Accupril | QUINAPRIL)
Copy SMILES
Copy InChI
Affinity Data
IC50: 9.40E+4nM
Assay Description:
Inhibition of human BSEP overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-taurocholate in presence of ATP measured after 15 to ...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
ATP-binding cassette sub-family C member 4
(Homo sapiens (Human))
Amgen
Curated by
ChEMBL
Ligand
BDBM50368166
(Accupril | QUINAPRIL)
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Affinity Data
IC50: >1.33E+5nM
Assay Description:
Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
ATP-binding cassette sub-family C member 3
(Homo sapiens (Human))
Amgen
Curated by
ChEMBL
Ligand
BDBM50368166
(Accupril | QUINAPRIL)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.33E+5nM
Assay Description:
Inhibition of human MRP3 overexpressed in Sf9 insect cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI