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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 7 hits in this display   

TargetProthrombin(Homo sapiens (Human))
University Of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50253817(CHEMBL460144 | Ethyl 2-(benzyl{2-[(4-carbamimidoyl...)
Affinity DataKi:  42nMAssay Description:Inhibition of thrombin using S-2238 as substrate preincubated for 15 mins prior substrate addition measured for every 10 secs by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
University Of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50253817(CHEMBL460144 | Ethyl 2-(benzyl{2-[(4-carbamimidoyl...)
Affinity DataKi:  110nMAssay Description:Inhibition of thrombin (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
University Of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50253817(CHEMBL460144 | Ethyl 2-(benzyl{2-[(4-carbamimidoyl...)
Affinity DataKi:  1.12E+5nMAssay Description:Inhibition of factor 10a (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
University Of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50253817(CHEMBL460144 | Ethyl 2-(benzyl{2-[(4-carbamimidoyl...)
Affinity DataKi:  1.12E+5nMAssay Description:Inhibition of factor 10a using S-2222 as substrate preincubated for 15 mins prior substrate addition measured for every 10 secs by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb(Homo sapiens (Human))
University Of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50253817(CHEMBL460144 | Ethyl 2-(benzyl{2-[(4-carbamimidoyl...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of fibrinogen binding to human platelet GPIIb/IIIa receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
University Of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50253817(CHEMBL460144 | Ethyl 2-(benzyl{2-[(4-carbamimidoyl...)
Affinity DataIC50:  5.20E+4nMAssay Description:Displacement of biotinylated fibrinogen from human alpha2b-beta3 receptor after 2 hrs by chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
University Of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50253817(CHEMBL460144 | Ethyl 2-(benzyl{2-[(4-carbamimidoyl...)
Affinity DataIC50: >1.00E+5nMAssay Description:Displacement of biotinylated fibrinogen from human alpha5-beta3 receptor after 2 hrs by chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed