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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
7
hits in this display
Target
Prothrombin
(Homo sapiens (Human))
University Of Ljubljana
Curated by
ChEMBL
Ligand
BDBM50253817
(CHEMBL460144 | Ethyl 2-(benzyl{2-[(4-carbamimidoyl...)
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Affinity Data
Ki: 42nM
Assay Description:
Inhibition of thrombin using S-2238 as substrate preincubated for 15 mins prior substrate addition measured for every 10 secs by spectrophotometry
More data for this Ligand-Target Pair
Target Info
PDB
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UniProtKB/SwissProt
antibodypedia
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Ligand Info
CHEMBL
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PC sid
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Article
PubMed
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Target
Prothrombin
(Homo sapiens (Human))
University Of Ljubljana
Curated by
ChEMBL
Ligand
BDBM50253817
(CHEMBL460144 | Ethyl 2-(benzyl{2-[(4-carbamimidoyl...)
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Affinity Data
Ki: 110nM
Assay Description:
Inhibition of thrombin (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
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UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
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In Depth
Details
Article
PubMed
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Target
Coagulation factor X
(Homo sapiens (Human))
University Of Ljubljana
Curated by
ChEMBL
Ligand
BDBM50253817
(CHEMBL460144 | Ethyl 2-(benzyl{2-[(4-carbamimidoyl...)
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Affinity Data
Ki: 1.12E+5nM
Assay Description:
Inhibition of factor 10a (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
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Ligand Info
CHEMBL
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Article
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Target
Coagulation factor X
(Homo sapiens (Human))
University Of Ljubljana
Curated by
ChEMBL
Ligand
BDBM50253817
(CHEMBL460144 | Ethyl 2-(benzyl{2-[(4-carbamimidoyl...)
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Affinity Data
Ki: 1.12E+5nM
Assay Description:
Inhibition of factor 10a using S-2222 as substrate preincubated for 15 mins prior substrate addition measured for every 10 secs by spectrophotometry
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
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In Depth
Details
Article
PubMed
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Target
Integrin alpha-IIb
(Homo sapiens (Human))
University Of Ljubljana
Curated by
ChEMBL
Ligand
BDBM50253817
(CHEMBL460144 | Ethyl 2-(benzyl{2-[(4-carbamimidoyl...)
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Affinity Data
IC50: 2.00E+3nM
Assay Description:
Inhibition of fibrinogen binding to human platelet GPIIb/IIIa receptor
More data for this Ligand-Target Pair
Target Info
PDB
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KEGG
UniProtKB/SwissProt
B.MOAD
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antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
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In Depth
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Article
PubMed
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Target
Integrin alpha-IIb/beta-3
(Homo sapiens (Human))
University Of Ljubljana
Curated by
ChEMBL
Ligand
BDBM50253817
(CHEMBL460144 | Ethyl 2-(benzyl{2-[(4-carbamimidoyl...)
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Affinity Data
IC50: 5.20E+4nM
Assay Description:
Displacement of biotinylated fibrinogen from human alpha2b-beta3 receptor after 2 hrs by chemiluminescence assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Integrin alpha-V/beta-3
(Homo sapiens (Human))
University Of Ljubljana
Curated by
ChEMBL
Ligand
BDBM50253817
(CHEMBL460144 | Ethyl 2-(benzyl{2-[(4-carbamimidoyl...)
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Affinity Data
IC50: >1.00E+5nM
Assay Description:
Displacement of biotinylated fibrinogen from human alpha5-beta3 receptor after 2 hrs by chemiluminescence assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI