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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
3
hits in this display
Target
Acetylcholinesterase
(Homo sapiens (Human))
Csic
Ligand
BDBM29401
(tacrine-dihydropyridine hybrid (tacripyrine), 12)
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Affinity Data
IC50: 45nM
pH: 7.2 T: 2°C
Assay Description:
The inhibitory activity of the compounds towards hAChE was determined following the method of Ellman using AChE from human serum and acetylthiocholin...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Acetylcholinesterase
(Electrophorus electricus (Electric eel))
Csic
Ligand
BDBM29401
(tacrine-dihydropyridine hybrid (tacripyrine), 12)
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Affinity Data
IC50: 103nM
Assay Description:
The inhibitory activity of the compounds towards AChE was determined following the spectrophotometric method of Rappaport using purified AChE from Ee...
More data for this Ligand-Target Pair
Target Info
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cholinesterase
(Homo sapiens (Human))
Csic
Ligand
BDBM29401
(tacrine-dihydropyridine hybrid (tacripyrine), 12)
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Copy InChI
Affinity Data
IC50: >1.00E+5nM
pH: 7.2 T: 2°C
Assay Description:
The inhibitory activity of the compounds towards BuChE was determined following the method of Ellman using BuChE from human serum and butyrylthiochol...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI