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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetAcetylcholinesterase(Homo sapiens (Human))
Csic

LigandPNGBDBM29401(tacrine-dihydropyridine hybrid (tacripyrine), 12)
Affinity DataIC50:  45nMpH: 7.2 T: 2°CAssay Description:The inhibitory activity of the compounds towards hAChE was determined following the method of Ellman using AChE from human serum and acetylthiocholin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Csic

LigandPNGBDBM29401(tacrine-dihydropyridine hybrid (tacripyrine), 12)
Affinity DataIC50:  103nMAssay Description:The inhibitory activity of the compounds towards AChE was determined following the spectrophotometric method of Rappaport using purified AChE from Ee...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Csic

LigandPNGBDBM29401(tacrine-dihydropyridine hybrid (tacripyrine), 12)
Affinity DataIC50: >1.00E+5nMpH: 7.2 T: 2°CAssay Description:The inhibitory activity of the compounds towards BuChE was determined following the method of Ellman using BuChE from human serum and butyrylthiochol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed