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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
6
hits in this display
Target
Acetylcholinesterase
(Electrophorus electricus (Electric eel))
Csic
Ligand
BDBM29393
(CHEMBL219400 | tacrine-dihydropyridine hybrid (tac...)
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Affinity Data
IC50: 304nM
Assay Description:
The inhibitory activity of the compounds towards AChE was determined following the spectrophotometric method of Rappaport using purified AChE from Ee...
More data for this Ligand-Target Pair
Target Info
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Acetylcholinesterase
(Electrophorus electricus (Electric eel))
Csic
Ligand
BDBM29393
(CHEMBL219400 | tacrine-dihydropyridine hybrid (tac...)
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Copy InChI
Affinity Data
IC50: 304nM
Assay Description:
Inhibition of Electrophorus electricus AChE
More data for this Ligand-Target Pair
Target Info
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Acetylcholinesterase
(Homo sapiens (Human))
Laboratorio De Radicales Libres (Iqog, Csic)
Curated by
ChEMBL
Ligand
BDBM29393
(CHEMBL219400 | tacrine-dihydropyridine hybrid (tac...)
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Affinity Data
IC50: 338nM
Assay Description:
Inhibition of human erythrocyte AChE
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Acetylcholinesterase
(Homo sapiens (Human))
Laboratorio De Radicales Libres (Iqog, Csic)
Curated by
ChEMBL
Ligand
BDBM29393
(CHEMBL219400 | tacrine-dihydropyridine hybrid (tac...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 338nM
pH: 7.2 T: 2°C
Assay Description:
The inhibitory activity of the compounds towards hAChE was determined following the method of Ellman using AChE from human serum and acetylthiocholin...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cholinesterase
(Homo sapiens (Human))
Laboratorio De Radicales Libres (Iqog, Csic)
Curated by
ChEMBL
Ligand
BDBM29393
(CHEMBL219400 | tacrine-dihydropyridine hybrid (tac...)
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Affinity Data
IC50: 4.80E+3nM
Assay Description:
Inhibition of human serum BuChE
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cholinesterase
(Homo sapiens (Human))
Laboratorio De Radicales Libres (Iqog, Csic)
Curated by
ChEMBL
Ligand
BDBM29393
(CHEMBL219400 | tacrine-dihydropyridine hybrid (tac...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 4.80E+3nM
pH: 7.2 T: 2°C
Assay Description:
The inhibitory activity of the compounds towards BuChE was determined following the method of Ellman using BuChE from human serum and butyrylthiochol...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI