Compile Data Set for Download or QSAR
maximum 50k data

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 6 hits in this display   

TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Csic

LigandPNGBDBM29393(CHEMBL219400 | tacrine-dihydropyridine hybrid (tac...)
Affinity DataIC50:  304nMAssay Description:The inhibitory activity of the compounds towards AChE was determined following the spectrophotometric method of Rappaport using purified AChE from Ee...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Csic

LigandPNGBDBM29393(CHEMBL219400 | tacrine-dihydropyridine hybrid (tac...)
Affinity DataIC50:  304nMAssay Description:Inhibition of Electrophorus electricus AChEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Laboratorio De Radicales Libres (Iqog, Csic)

Curated by ChEMBL
LigandPNGBDBM29393(CHEMBL219400 | tacrine-dihydropyridine hybrid (tac...)
Affinity DataIC50:  338nMAssay Description:Inhibition of human erythrocyte AChEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Laboratorio De Radicales Libres (Iqog, Csic)

Curated by ChEMBL
LigandPNGBDBM29393(CHEMBL219400 | tacrine-dihydropyridine hybrid (tac...)
Affinity DataIC50:  338nMpH: 7.2 T: 2°CAssay Description:The inhibitory activity of the compounds towards hAChE was determined following the method of Ellman using AChE from human serum and acetylthiocholin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Laboratorio De Radicales Libres (Iqog, Csic)

Curated by ChEMBL
LigandPNGBDBM29393(CHEMBL219400 | tacrine-dihydropyridine hybrid (tac...)
Affinity DataIC50:  4.80E+3nMAssay Description:Inhibition of human serum BuChEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Laboratorio De Radicales Libres (Iqog, Csic)

Curated by ChEMBL
LigandPNGBDBM29393(CHEMBL219400 | tacrine-dihydropyridine hybrid (tac...)
Affinity DataIC50:  4.80E+3nMpH: 7.2 T: 2°CAssay Description:The inhibitory activity of the compounds towards BuChE was determined following the method of Ellman using BuChE from human serum and butyrylthiochol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed