Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Sirtris A Gsk

Curated by ChEMBL

LigandBDBM50396055(CHEMBL2170193)Copy SMILESCopy InChI

Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of SIRT1More data for this Ligand-Target Pair

Target InfoPDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Sirtris A Gsk

Curated by ChEMBL

LigandBDBM50396055(CHEMBL2170193)Copy SMILESCopy InChI

Affinity DataIC50:  6.50E+4nMAssay Description:Inhibition of SIRT2More data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetNAD-dependent protein deacetylase sirtuin-3, mitochondrial(Homo sapiens (Human))
Sirtris A Gsk

Curated by ChEMBL

LigandBDBM50396055(CHEMBL2170193)Copy SMILESCopy InChI

Affinity DataIC50: >3.00E+5nMAssay Description:Inhibition of SIRT3More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI