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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
4
hits in this display
Target
Squalene synthase
(Rattus norvegicus)
TBA
Curated by
ChEMBL
Ligand
BDBM50075719
(3-[3-Allyl-4-(3-hydroxy-1-aza-bicyclo[2.2.2]oct-3-...)
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Affinity Data
Ki: 6nM
Assay Description:
Tested for its inhibitory activity against rat microsomal quinuclidine squalene synthase (SQS)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
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Target
Squalene synthase
(Homo sapiens (Human))
TBA
Curated by
ChEMBL
Ligand
BDBM50075719
(3-[3-Allyl-4-(3-hydroxy-1-aza-bicyclo[2.2.2]oct-3-...)
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Copy InChI
Affinity Data
Ki: 43nM
Assay Description:
Tested for its inhibitory activity against human microsomal quinuclidine squalene synthase (SQS)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
Copy BDB DOI
Target
Squalene synthase
(Rattus norvegicus)
TBA
Curated by
ChEMBL
Ligand
BDBM50075719
(3-[3-Allyl-4-(3-hydroxy-1-aza-bicyclo[2.2.2]oct-3-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 6nM
Assay Description:
Compound was measured for the inhibition of rat microsomal squalene synthase enzyme
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
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Target
Lanosterol synthase
(Rattus norvegicus)
Zeneca Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50075719
(3-[3-Allyl-4-(3-hydroxy-1-aza-bicyclo[2.2.2]oct-3-...)
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Copy InChI
Affinity Data
IC50: >100nM
Assay Description:
Inhibition of compound was measured on rat microsomal Oxidosqualene-lanosterol cyclase
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI