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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
3
hits in this display
Target
Polyunsaturated fatty acid 5-lipoxygenase
(Homo sapiens (Human))
University Of Naples
Curated by
ChEMBL
Ligand
BDBM50016516
(CHEMBL3260691)
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Affinity Data
IC50: 230nM
Assay Description:
Inhibition of 5-LO in human polymorphonuclear leukocytes assessed as inhibition of LTB4 production from arachidonic acid preincubated for 15 mins by ...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Polyunsaturated fatty acid 5-lipoxygenase
(Homo sapiens (Human))
University Of Naples
Curated by
ChEMBL
Ligand
BDBM50016516
(CHEMBL3260691)
Copy SMILES
Copy InChI
Affinity Data
IC50: 700nM
Assay Description:
Inhibition of human recombinant 5-LO expressed in Escherichia coli BL21 using arachidonic acid as substrate preincubated for 5 to 10 mins by HPLC ana...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Polyunsaturated fatty acid lipoxygenase ALOX15
(Homo sapiens (Human))
University Of Naples
Curated by
ChEMBL
Ligand
BDBM50016516
(CHEMBL3260691)
Copy SMILES
Copy InChI
Affinity Data
IC50: 8.20E+3nM
Assay Description:
Inhibition of 15-LO in human polymorphonuclear leukocytes assessed as inhibition of 15-H(P)ETE production from arachidonic acid preincubated for 15 m...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI