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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
8
hits in this display
Target
Serine/threonine-protein kinase mTOR
(Homo sapiens (Human))
University Of Edinburgh
Curated by
ChEMBL
Ligand
BDBM50184774
(CHEMBL3799221)
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Affinity Data
IC50: 328nM
Assay Description:
Inhibition of human mTOR using poly[Glu,Tyr]4:1 as substrate in presence of [gamma-33P]ATP
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Tyrosine-protein kinase Yes
(Homo sapiens (Human))
University Of Edinburgh
Curated by
ChEMBL
Ligand
BDBM50184774
(CHEMBL3799221)
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Affinity Data
IC50: 566nM
Assay Description:
Inhibition of human YES using poly[Glu,Tyr]4:1 as substrate in presence of [gamma-33P] ATP
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Proto-oncogene tyrosine-protein kinase receptor Ret
(Homo sapiens (Human))
University Of Edinburgh
Curated by
ChEMBL
Ligand
BDBM50184774
(CHEMBL3799221)
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Affinity Data
IC50: 598nM
Assay Description:
Inhibition of human RET using poly[Glu,Tyr]4:1 as substrate in presence of [gamma-33P]ATP
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Tyrosine-protein kinase ABL1
(Homo sapiens (Human))
University Of Edinburgh
Curated by
ChEMBL
Ligand
BDBM50184774
(CHEMBL3799221)
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Affinity Data
IC50: 1.21E+3nM
Assay Description:
Inhibition of human ABL using EAIYAAPFAKKK as substrate in presence of [gamma-33P]ATP
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Tyrosine-protein kinase Fyn
(Homo sapiens (Human))
University Of Edinburgh
Curated by
ChEMBL
Ligand
BDBM50184774
(CHEMBL3799221)
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Affinity Data
IC50: 1.23E+3nM
Assay Description:
Inhibition of human FYN using poly[Glu,Tyr]4:1 as substrate in presence of [gamma-33P]ATP
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human))
University Of Edinburgh
Curated by
ChEMBL
Ligand
BDBM50184774
(CHEMBL3799221)
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Affinity Data
IC50: 2.45E+3nM
Assay Description:
Inhibition of C-terminal His-tagged full length human SRC expressed in insect cells preincubated for 20 mins using poly[Glu,Tyr]4:1 as substrate meas...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Platelet-derived growth factor receptor alpha
(Homo sapiens (Human))
University Of Edinburgh
Curated by
ChEMBL
Ligand
BDBM50184774
(CHEMBL3799221)
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Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of human PDGFRalpha using poly[Glu,Tyr]4:1 as substrate in presence of [gamma-33P]ATP
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Mast/stem cell growth factor receptor Kit
(Homo sapiens (Human))
University Of Edinburgh
Curated by
ChEMBL
Ligand
BDBM50184774
(CHEMBL3799221)
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Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of human KIT using poly[Glu,Tyr]4:1 as substrate in presence of [gamma-33P]ATP
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI