Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 7 hits in this display   

TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Amgen

Curated by ChEMBL

LigandBDBM50446514(CHEMBL3110076)Copy SMILESCopy InChI

Affinity DataIC50:  8.20nMAssay Description:Inhibition of human ACC2 expressed in CHOK1 cells assessed as acetylCoA to malonylCoA conversion after 1 hr by LC-MS/MS analysisMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Amgen

Curated by ChEMBL

LigandBDBM50446514(CHEMBL3110076)Copy SMILESCopy InChI

Affinity DataIC50:  54nMAssay Description:Inhibition of human ACC2 assessed as acetylCoA to malonylCoA conversion after 10 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetAcetyl-CoA carboxylase 2(Mus musculus)
Amgen

Curated by ChEMBL

LigandBDBM50446514(CHEMBL3110076)Copy SMILESCopy InChI

Affinity DataIC50:  89nMAssay Description:Inhibition of mouse ACC2More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetAcetyl-CoA carboxylase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL

LigandBDBM50446514(CHEMBL3110076)Copy SMILESCopy InChI

Affinity DataIC50:  193nMAssay Description:Inhibition of human ACC1 assessed as acetylCoA to malonylCoA conversion after 10 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetAcetyl-CoA carboxylase 1(Mus musculus)
Amgen

Curated by ChEMBL

LigandBDBM50446514(CHEMBL3110076)Copy SMILESCopy InChI

Affinity DataIC50:  427nMAssay Description:Inhibition of mouse ACC1More data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetCytochrome P450 3A4(Homo sapiens (Human))
Amgen

Curated by ChEMBL

LigandBDBM50446514(CHEMBL3110076)Copy SMILESCopy InChI

Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of human CYP3A4More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetCytochrome P450 2D6(Homo sapiens (Human))
Amgen

Curated by ChEMBL

LigandBDBM50446514(CHEMBL3110076)Copy SMILESCopy InChI

Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of human CYP2D6More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI