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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
5
hits in this display
Target
ALK tyrosine kinase receptor
(Homo sapiens (Human))
Chugai Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50344644
(8-(2-(diethylamino)ethoxy)-3-ethoxy-6,6-dimethylbe...)
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Affinity Data
Ki: 170nM
Assay Description:
Competitive inhibition of ALK phosphorylation by Lineweaver-Burk plot analysis
Checked by Author
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
ALK tyrosine kinase receptor
(Homo sapiens (Human))
Chugai Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50344644
(8-(2-(diethylamino)ethoxy)-3-ethoxy-6,6-dimethylbe...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.34E+3nM
Assay Description:
Inhibition of ALK (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
ALK tyrosine kinase receptor
(Homo sapiens (Human))
Chugai Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50344644
(8-(2-(diethylamino)ethoxy)-3-ethoxy-6,6-dimethylbe...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.34E+3nM
Assay Description:
Inhibition of ALK assessed as biotin-EGPWLEEEEEAYGWMDF peptide phosphorylation by TR-FRET assay
Checked by Author
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Hepatocyte growth factor receptor
(Homo sapiens (Human))
Zhejiang University
Curated by
ChEMBL
Ligand
BDBM50344644
(8-(2-(diethylamino)ethoxy)-3-ethoxy-6,6-dimethylbe...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >5.00E+4nM
Assay Description:
Inhibition of c-Met (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Hepatocyte growth factor receptor
(Homo sapiens (Human))
Zhejiang University
Curated by
ChEMBL
Ligand
BDBM50344644
(8-(2-(diethylamino)ethoxy)-3-ethoxy-6,6-dimethylbe...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >5.00E+4nM
Assay Description:
Inhibition of c-Met assessed as biotin-EGPWLEEEEEAYGWMDF peptide phosphorylation by TR-FRET assay
Checked by Author
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI