Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetProteasome subunit beta type-8(Homo sapiens (Human))
Hungarian Academy Of Sciences

Curated by ChEMBL

LigandBDBM50436622(CHEMBL568708)Copy SMILESCopy InChI

Affinity DataIC50:  9.00E+3nMAssay Description:Inhibition of human chymotrypsin-like beta 5i subunit of iCP using suc-LLVY-AMC as flurogenic substrate for 90 mins by fluorescence-based assayMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankGoogleScholar

Ligand InfoPurchaseCHEMBLPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI

Target5'-AMP-activated protein kinase catalytic subunit alpha-2(Rattus norvegicus)
Bar-Ilan University

Curated by ChEMBL

LigandBDBM50436622(CHEMBL568708)Copy SMILESCopy InChI

Affinity DataEC50:  7.61E+4nMAssay Description:Activation of AMPK in rat L6 cells assessed as increase of [3H]dGlc uptake after 5 hrsMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADGoogleScholar

Ligand InfoPurchaseCHEMBLPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI