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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 4 hits in this display   

TargetApoptosis regulator BAX(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50078022(CHEMBL3417402)
Affinity DataKi:  800nMAssay Description:Displacement of FITC-BIM from recombinant N-terminal GST-tagged human BAX expressed in Escherichia coli after 30 mins by fluorescence polarization as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50078022(CHEMBL3417402)
Affinity DataKi:  1.20E+4nMAssay Description:Displacement of FITC-BIM from recombinant human Bcl-2 expressed in Escherichia coli after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50078022(CHEMBL3417402)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of FITC-BIM from recombinant human Bcl-XL expressed in Escherichia coli after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetApoptosis regulator BAX(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50078022(CHEMBL3417402)
Affinity DataEC50:  700nMAssay Description:Activation of Bax in human HuH7 cells assessed as inhibition of mitochondrial accumulation of fluorescent probe Mitotracker Red after 12 to 72 hrs by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed