Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)
Found 20 hits in this display
BDBM202809(US10245267, Example 156 | US10709712, Example 235 ...)
BDBM202809(US10245267, Example 156 | US10709712, Example 235 ...)
BDBM202809(US10245267, Example 156 | US10709712, Example 235 ...)
BDBM202809(US10245267, Example 156 | US10709712, Example 235 ...)
IC50: 0.400nMAssay Description:C-Raf TR refers to a truncated C-Raf protein, a Δ1-324 deletion mutant.C-Raf FL refers to the full-length C-Raf protein.Full length MEK1 with an...More data for this Ligand-Target Pair
BDBM202809(US10245267, Example 156 | US10709712, Example 235 ...)
IC50: 0.400nMAssay Description:Raf and biotinylated Mek, kinase dead, were combined at 2× final concentrations in assay buffer (50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% BSA and 1 mM ...More data for this Ligand-Target Pair
BDBM202809(US10245267, Example 156 | US10709712, Example 235 ...)
IC50: 0.400nMpH: 7.5 T: 2°CAssay Description:Raf and biotinylated Mek, kinase dead, were combined at 2x final concentrations in assay buffer (50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% BSA and 1 mM ...More data for this Ligand-Target Pair
BDBM202809(US10245267, Example 156 | US10709712, Example 235 ...)
BDBM202809(US10245267, Example 156 | US10709712, Example 235 ...)
IC50: 0.415nMAssay Description:C-Raf TR refers to a truncated C-Raf protein, a Δ1-324 deletion mutant.C-Raf FL refers to the full-length C-Raf protein.Full length MEK1 with an...More data for this Ligand-Target Pair
BDBM202809(US10245267, Example 156 | US10709712, Example 235 ...)
IC50: 0.415nMAssay Description:Raf and biotinylated Mek, kinase dead, were combined at 2× final concentrations in assay buffer (50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% BSA and 1 mM ...More data for this Ligand-Target Pair
BDBM202809(US10245267, Example 156 | US10709712, Example 235 ...)
IC50: 0.420nMpH: 7.5 T: 2°CAssay Description:Raf and biotinylated Mek, kinase dead, were combined at 2x final concentrations in assay buffer (50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% BSA and 1 mM ...More data for this Ligand-Target Pair
BDBM202809(US10245267, Example 156 | US10709712, Example 235 ...)
IC50: 1nMpH: 7.5 T: 2°CAssay Description:Raf and biotinylated Mek, kinase dead, were combined at 2x final concentrations in assay buffer (50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% BSA and 1 mM ...More data for this Ligand-Target Pair
BDBM202809(US10245267, Example 156 | US10709712, Example 235 ...)
IC50: 1nMAssay Description:C-Raf TR refers to a truncated C-Raf protein, a Δ1-324 deletion mutant.C-Raf FL refers to the full-length C-Raf protein.Full length MEK1 with an...More data for this Ligand-Target Pair
BDBM202809(US10245267, Example 156 | US10709712, Example 235 ...)
IC50: 1nMAssay Description:Raf and biotinylated Mek, kinase dead, were combined at 2× final concentrations in assay buffer (50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% BSA and 1 mM ...More data for this Ligand-Target Pair
BDBM202809(US10245267, Example 156 | US10709712, Example 235 ...)
IC50: 2.48nMpH: 7.5 T: 2°CAssay Description:Raf and biotinylated Mek, kinase dead, were combined at 2x final concentrations in assay buffer (50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% BSA and 1 mM ...More data for this Ligand-Target Pair
BDBM202809(US10245267, Example 156 | US10709712, Example 235 ...)
IC50: 2.48nMAssay Description:Raf and biotinylated Mek, kinase dead, were combined at 2× final concentrations in assay buffer (50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% BSA and 1 mM ...More data for this Ligand-Target Pair
BDBM202809(US10245267, Example 156 | US10709712, Example 235 ...)
IC50: 2.48nMAssay Description:C-Raf TR refers to a truncated C-Raf protein, a Δ1-324 deletion mutant.C-Raf FL refers to the full-length C-Raf protein.Full length MEK1 with an...More data for this Ligand-Target Pair
BDBM202809(US10245267, Example 156 | US10709712, Example 235 ...)
IC50: 2.48nMpH: 7.5 T: 2°CAssay Description:Final assay conditions were 4 pM cRaf, 3 uM ATP, 10 nM biotin tagged MEK1 kinase dead protein substrate. Reactions were performed in Greiner384 well ...More data for this Ligand-Target Pair
BDBM202809(US10245267, Example 156 | US10709712, Example 235 ...)
IC50: 2.5nMAssay Description:C-Raf TR refers to a truncated C-Raf protein, a Δ1-324 deletion mutant.C-Raf FL refers to the full-length C-Raf protein.Full length MEK1 with an...More data for this Ligand-Target Pair
BDBM202809(US10245267, Example 156 | US10709712, Example 235 ...)
IC50: 2.5nMAssay Description:Raf and biotinylated Mek, kinase dead, were combined at 2× final concentrations in assay buffer (50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% BSA and 1 mM ...More data for this Ligand-Target Pair
BDBM202809(US10245267, Example 156 | US10709712, Example 235 ...)
IC50: 2.5nMpH: 7.5 T: 2°CAssay Description:Raf and biotinylated Mek, kinase dead, were combined at 2x final concentrations in assay buffer (50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% BSA and 1 mM ...More data for this Ligand-Target Pair