Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Plexxikon

US Patent

LigandBDBM174926(US9096593, P-2202)Copy SMILESCopy InChI

Affinity DataIC50: >100nMpH: 7.5Assay Description:In one assay the biochemical activity IC50 values are determined with respect to inhibition of c-Kit kinase activity, where inhibition of phosphoryla...More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoPC cidPC sidSimilars

In DepthDetails US Patent
Copy BDB DOI

TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Plexxikon

US Patent

LigandBDBM174926(US9096593, P-2202)Copy SMILESCopy InChI

Affinity DataIC50: <100nMpH: 7.5 T: 2°CAssay Description:In one assay the biochemical activity IC50 values are determined with respect to inhibition of Fms kinase activity, where inhibition of phosphorylati...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoPC cidPC sidSimilars

In DepthDetails US Patent
Copy BDB DOI