Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Eisai

Curated by ChEMBL

LigandBDBM50037041(2-Amino-7-ethyl-5-methoxy-4-pyridin-3-ylmethyl-ben...)Copy SMILESCopy InChI

Affinity DataIC50:  150nMAssay Description:Inhibitory activity against the production of leukotriene B4 (LTB4) in glycogen-induced peritoneal cells of ratMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetThromboxane-A synthase(Rattus norvegicus)
Eisai

Curated by ChEMBL

LigandBDBM50037041(2-Amino-7-ethyl-5-methoxy-4-pyridin-3-ylmethyl-ben...)Copy SMILESCopy InChI

Affinity DataIC50:  180nMAssay Description:Inhibitory activity against the production of thromboxane B2 (TXB2) in glycogen-induced peritoneal cells of ratMore data for this Ligand-Target Pair

Target InfoReactome pathwayKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI