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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
3
hits in this display
Target
Beta-2 adrenergic receptor
(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by
ChEMBL
Ligand
BDBM50318154
(8-Hydroxy-5-[(R)-1-hydroxy-2-(4,7-diethylindan-2-y...)
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Affinity Data
Ki: 692nM
Assay Description:
Displacement of [125I]cyanopindolol from human recombinant beta2 adrenergic receptor expressed in CHO cells by filtration assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Beta-2 adrenergic receptor
(GUINEA PIG)
Novartis Institutes For Biomedical Research
Curated by
ChEMBL
Ligand
BDBM50318154
(8-Hydroxy-5-[(R)-1-hydroxy-2-(4,7-diethylindan-2-y...)
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Affinity Data
IC50: 75nM
Assay Description:
Agonist activity at beta2 adrenergic receptor in guinea pig tracheal strip assessed as inhibition of electrically-induced bronchocontractile response...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Beta-2 adrenergic receptor
(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by
ChEMBL
Ligand
BDBM50318154
(8-Hydroxy-5-[(R)-1-hydroxy-2-(4,7-diethylindan-2-y...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 115nM
Assay Description:
Agonist activity at human beta2 adrenergic receptor assessed as increase in cAMP level by whole cell assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI