Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetAngiotensin-converting enzyme(Homo sapiens (Human))
Santen Pharmaceutical

Curated by ChEMBL

LigandBDBM50266170((R)-3-(4-ethylbenzylthio)-2-((S)-3-mercapto-2-meth...)Copy SMILESCopy InChI

Affinity DataIC50:  21nMAssay Description:Inhibition of angiotensin-converting enzyme (unknown origin) in whole blood by HPLCMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetLeukotriene A-4 hydrolase(Cavia porcellus)
Santen Pharmaceutical

Curated by ChEMBL

LigandBDBM50266170((R)-3-(4-ethylbenzylthio)-2-((S)-3-mercapto-2-meth...)Copy SMILESCopy InChI

Affinity DataIC50:  280nMAssay Description:Inhibition of LTA4 hydrolase in guinea pig lung assessed as inhibition of LTB4 productionMore data for this Ligand-Target Pair

Target InfoPDBMMDB
UniProtKB/SwissProt
B.MOADGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI