Compile Data Set for Download or QSAR
maximum 50k data

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 4 hits in this display   

TargetUrea transporter 1(Mus musculus)
San Francisco State University

Curated by ChEMBL
LigandPNGBDBM50322183(3-(4-ethylphenylsulfonyl)-N-(3-methoxypropyl)thien...)
Affinity DataIC50:  212nMAssay Description:Inhibition of UT-B in wild type CD1 mouse erythrocyte assessed as hemolysis after 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50322183(3-(4-ethylphenylsulfonyl)-N-(3-methoxypropyl)thien...)
Affinity DataIC50: >5.00E+3nMAssay Description:Antagonist activity at human recombinant 5HT6 receptor expressed in HEK293 cells assessed as inhibition of serotonin-induced cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrea transporter 1(Rattus norvegicus (Rat))
University of California San Francisco

LigandPNGBDBM50322183(3-(4-ethylphenylsulfonyl)-N-(3-methoxypropyl)thien...)
Affinity DataIC50:  2.80E+4nMAssay Description:Erythrocyte suspension (100 µL) was added to each well of a 96-well microplate to which test compounds were added. After 15 min incubation, 20 &...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrea transporter 2(Rattus norvegicus (Rat))
University of California San Francisco

LigandPNGBDBM50322183(3-(4-ethylphenylsulfonyl)-N-(3-methoxypropyl)thien...)
Affinity DataIC50: >5.00E+4nMAssay Description:The urea concentration dependence of UT-A1 inhibition was studied from inhibitor concentration response data (0.3 - 60 µM) using different of ur...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed