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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
4
hits in this display
Target
Urea transporter 1
(Mus musculus)
San Francisco State University
Curated by
ChEMBL
Ligand
BDBM50322183
(3-(4-ethylphenylsulfonyl)-N-(3-methoxypropyl)thien...)
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Affinity Data
IC50: 212nM
Assay Description:
Inhibition of UT-B in wild type CD1 mouse erythrocyte assessed as hemolysis after 10 mins
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
5-hydroxytryptamine receptor 6
(Homo sapiens (Human))
Chemical Diversity Research Institute
Curated by
ChEMBL
Ligand
BDBM50322183
(3-(4-ethylphenylsulfonyl)-N-(3-methoxypropyl)thien...)
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Affinity Data
IC50: >5.00E+3nM
Assay Description:
Antagonist activity at human recombinant 5HT6 receptor expressed in HEK293 cells assessed as inhibition of serotonin-induced cAMP production
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Urea transporter 1
(Rattus norvegicus (Rat))
University of California San Francisco
Ligand
BDBM50322183
(3-(4-ethylphenylsulfonyl)-N-(3-methoxypropyl)thien...)
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Affinity Data
IC50: 2.80E+4nM
Assay Description:
Erythrocyte suspension (100 µL) was added to each well of a 96-well microplate to which test compounds were added. After 15 min incubation, 20 &...
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Urea transporter 2
(Rattus norvegicus (Rat))
University of California San Francisco
Ligand
BDBM50322183
(3-(4-ethylphenylsulfonyl)-N-(3-methoxypropyl)thien...)
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Affinity Data
IC50: >5.00E+4nM
Assay Description:
The urea concentration dependence of UT-A1 inhibition was studied from inhibitor concentration response data (0.3 - 60 µM) using different of ur...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI