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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
3
hits in this display
Target
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2
(Homo sapiens (Human))
Galapagos
US Patent
Ligand
BDBM193327
(US11072611, Compound 208 | US9670204, 208 4-(2-eth...)
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Affinity Data
IC50: 50nM
Assay Description:
TABLE VI: (UniProtKB/SwissProt Sequence ref Q13822) biochemical assay using the fluorogenic autotaxin substrate FS-3 as substrate. FS-3 is a doubly l...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2
(Homo sapiens (Human))
Galapagos
US Patent
Ligand
BDBM193327
(US11072611, Compound 208 | US9670204, 208 4-(2-eth...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+3nM
pH: 8.5 T: 2°C
Assay Description:
Compound IC50 values are determined in a hENPP2 (UniProtKB/SwissProt Sequence ref Q13822) biochemical assay using LPC as substrate. 5 μL of a di...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2
(Homo sapiens (Human))
Galapagos
US Patent
Ligand
BDBM193327
(US11072611, Compound 208 | US9670204, 208 4-(2-eth...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+3nM
Assay Description:
TABLE V: 5 μL of a dilution series of compound, starting from 20 μM highest concentration, 1/5 dilution, is added to the wells. hENPP2 is u...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI