Compile Data Set for Download or QSAR
maximum 50k data

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 5 hits in this display   

TargetMacrophage metalloelastase(Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM26572((3R,4R)-4-N-[4-({2-ethylpyrazolo[1,5-a]pyridin-3-y...)
Affinity DataKi:  327nMAssay Description:The compounds were tested for enzyme inhibition using fluorescence resonance energy transfer (FRET) assay. Fluorescence measurements were performed i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM26572((3R,4R)-4-N-[4-({2-ethylpyrazolo[1,5-a]pyridin-3-y...)
Affinity DataKi:  3.31E+3nMAssay Description:The compounds were tested for enzyme inhibition using fluorescence resonance energy transfer (FRET) assay. Fluorescence measurements were performed i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM26572((3R,4R)-4-N-[4-({2-ethylpyrazolo[1,5-a]pyridin-3-y...)
Affinity DataKi: >3.33E+3nM ΔG°: >-31.3kJ/molepH: 7.5 T: 2°CAssay Description:The compounds were tested for enzyme inhibition using fluorescence resonance energy transfer (FRET) assay. Fluorescence measurements were performed i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrilysin(Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM26572((3R,4R)-4-N-[4-({2-ethylpyrazolo[1,5-a]pyridin-3-y...)
Affinity DataKi: >6.37E+3nMAssay Description:The compounds were tested for enzyme inhibition using fluorescence resonance energy transfer (FRET) assay. Fluorescence measurements were performed i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Sus scrofa (pig))
Bristol-Myers Squibb

LigandPNGBDBM26572((3R,4R)-4-N-[4-({2-ethylpyrazolo[1,5-a]pyridin-3-y...)
Affinity DataIC50:  2nMpH: 7.5 T: 2°CAssay Description:The compounds were tested for enzyme inhibition using fluorescence resonance energy transfer (FRET) assay. Fluorescence measurements were performed i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed