Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 6 hits in this display   

TargetNociceptin receptor(Homo sapiens (Human))
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50083232(1-(1-Cyclooctylmethyl-piperidin-4-yl)-3-ethyl-1,3-...)
Affinity DataIC50:  6.80nMAssay Description:Inhibition of [125I]-Tyr14-nociceptin binding to human Opioid receptor like 1 (opioid receptor like 1) in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50083232(1-(1-Cyclooctylmethyl-piperidin-4-yl)-3-ethyl-1,3-...)
Affinity DataIC50:  20nMAssay Description:Antagonistic activity of the compound measured by GTPgammaS binding against Opioid receptor like 1 in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50083232(1-(1-Cyclooctylmethyl-piperidin-4-yl)-3-ethyl-1,3-...)
Affinity DataIC50:  440nMAssay Description:Binding affinity in CHO cells stably expressing cloned human Opioid receptor kappa 1 by displacing radioligand [3H]U-69593More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50083232(1-(1-Cyclooctylmethyl-piperidin-4-yl)-3-ethyl-1,3-...)
Affinity DataIC50:  950nMAssay Description:Inhibition of [3H]-diprenorphine binding to human Opioid receptor mu 1 in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50083232(1-(1-Cyclooctylmethyl-piperidin-4-yl)-3-ethyl-1,3-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of [3H][D-Ala2,D-Leu5]enkephalin binding to human Opioid receptor delta 1 in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50083232(1-(1-Cyclooctylmethyl-piperidin-4-yl)-3-ethyl-1,3-...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonistic activity of the compound measured by GTPgammaS binding against Opioid receptor like 1 in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed