Compile Data Set for Download or QSAR
maximum 50k data

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 4 hits in this display   

TargetAdenosine receptor A2a(Homo sapiens (Human))
Vernalis (R&D)

LigandPNGBDBM35837(pyrimidine-4-carboxamide, 119)
Affinity DataKi:  3.5nMAssay Description:Binding assays were performed in a total volume of 250 uL, containing radioligand, membranes and test compounds. Following 60 (A2B, A3) or 90 (A1, A2...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
Vernalis (R&D)

LigandPNGBDBM35837(pyrimidine-4-carboxamide, 119)
Affinity DataKi:  385nMAssay Description:Binding assays were performed in a total volume of 250 uL, containing radioligand, membranes and test compounds. Following 60 (A2B, A3) or 90 (A1, A2...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Vernalis (R&D)

LigandPNGBDBM35837(pyrimidine-4-carboxamide, 119)
Affinity DataKi:  741nMAssay Description:Binding assays were performed in a total volume of 250 uL, containing radioligand, membranes and test compounds. Following 60 (A2B, A3) or 90 (A1, A2...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2b(Homo sapiens (Human))
Vernalis (R&D)

LigandPNGBDBM35837(pyrimidine-4-carboxamide, 119)
Affinity DataKi:  1.30E+3nMAssay Description:Binding assays were performed in a total volume of 250 uL, containing radioligand, membranes and test compounds. Following 60 (A2B, A3) or 90 (A1, A2...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed