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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
2
hits in this display
Target
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex
(Mycobacterium tuberculosis)
Academia Sinica
US Patent
Ligand
BDBM188292
(US9073941, 620)
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Affinity Data
IC50: <40nM
pH: 7.0
Assay Description:
Mtb PDH (Lpd+DlaT+AceE) is provided by Dr. Bryk Ruslana. The assay was performed in a manner similar to that described in Bryk et al., Biochemistry (...
More data for this Ligand-Target Pair
Target Info
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
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PC sid
Similars
In Depth
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US Patent
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Target
Dihydrolipoyl dehydrogenase
(Mycobacterium tuberculosis)
Academia Sinica
US Patent
Ligand
BDBM188292
(US9073941, 620)
Copy SMILES
Copy InChI
Affinity Data
IC50: <40nM
pH: 7.0
Assay Description:
The assay was performed in a manner similar to that described in Bryk et al., Biochemistry (2010) 49:1616-1627 and modified for an online robotics sc...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
Similars
In Depth
Details
US Patent
Copy BDB DOI